Our Research Publications
Updated August 2025
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| Title | Authors | Year Sort ascending | Journal | Link to Article | Intended Audience | Purpose |
|---|---|---|---|---|---|---|
| Blood Donation Testing and the Safety of the Blood Supply | Goldman M, Drews SJ | 2022 | Practical Transfusion Medicine | View Blood Donation Testing and the Safety of the Blood Supply | Health care providers | Benchmarking and standard setting |
| FAQ: Canadian Blood Services platelet bacterial screening | Khandelwal A, Ramirez-Arcos S, Bigham M | 2022 | Blood.ca website | View FAQ: Canadian Blood Services platelet bacterial screening | Health care providers | Benchmarking and standard setting |
| FAQ : Le sang total déleucocyté à la Société canadienne du sang | Mack J | 2022 | Blood.ca website | View FAQ : Le sang total déleucocyté à la Société canadienne du sang | Health care providers | New or improved product or process |
| A Portrait of Cord Blood Units Distributed for Transplantation from Canadian Blood Services’ Cord Blood Bank: First Analysis | Parmar G, Green M, Mostert K, Lawless T, Dibdin N, Weiss J, Ganz K, Petraszko T, Seftel MD, Allan DS | 2022 | Curr Oncol | View A Portrait of Cord Blood Units Distributed for Transplantation from Canadian Blood Services’ Cord Blood Bank: First Analysis | Researchers | Benchmarking and standard setting |
| Circulaire d'information utilisation de composants sanguins humains: Sang total | Stewart T | 2022 | Blood.ca website | View Circulaire d'information utilisation de composants sanguins humains: Sang total | Health care providers | Benchmarking and standard setting |
| Babesia microti in a Canadian blood donor and lookback in a red blood cell recipient | Drews SJ, Van Caeseele P, Bullard J, Lindsay LR, Gaziano T, Zeller MP, Lane D, Ndao M, Allen VG, Boggild AK, O'Brien SF, Marko D, Musuka C, Almiski M, Bigham M | 2022 | Vox Sang | View Babesia microti in a Canadian blood donor and lookback in a red blood cell recipient | Health care providers | Clinical research |
| Hemolysis after high-dose intravenous immunoglobulin: An under-appreciated sequelae | Branch DR, Almizraq RJ, Bussel JB | 2022 | Am J Hematol | View Hemolysis after high-dose intravenous immunoglobulin: An under-appreciated sequelae | Researchers | Basic research |
| Prolonged Blood Storage and Risk of Posttransfusion Acute Kidney Injury | Adegboye J, Sapatnekar S, Mascha EJ, Shah K, Lioudis M, Essber H, Cohen B, Rivas E, Heddle NM, Eikelboom JW, Ellis MH, Sharon Y, Sinha R, Kurz A, Sessler DI | 2022 | Anesthesiology | View Prolonged Blood Storage and Risk of Posttransfusion Acute Kidney Injury | Researchers | Clinical research |
| Chapter 19. Pathogen-reduced platelets | Blais-Normandin I, Tordon B, Anani W, Ning S | 2022 | Clinical Guide to Transfusion | View Chapter 19. Pathogen-reduced platelets | Health care providers | Benchmarking and standard setting |
| Lessons Learned from the COVID-19 Pandemic and How Blood Operators Can Prepare for the Next Pandemic | Drews SJ, O’Brien SF | 2022 | Viruses | View Lessons Learned from the COVID-19 Pandemic and How Blood Operators Can Prepare for the Next Pandemic | Blood operators | New or improved product or process |
| A critical contribution in a time of crisis: Examining motivations and deterrents to COVID-19 convalescent plasma donation and future donation intentions among prospective Canadian donors | Holloway K, Campbell C, Ali R, Huyer LD, Hart D, Haw J, Brennenstuhl S, Grundy Q | 2022 | Transfus Med | View A critical contribution in a time of crisis: Examining motivations and deterrents to COVID-19 convalescent plasma donation and future donation intentions among prospective Canadian donors | Researchers | Ethical, legal & social implications research |
| Ex vivo enzymatic treatment converts blood type A donor lungs into universal blood type lungs | Wang A, Ribeiro RVP, Ali A, Brambate E, Abdelnour-Berchtold E, Michaelsen V, Zhang Y, Rahfeld P, Moon H, Gokhale H, Gazzalle A, Pal P, Liu M, Waddell TK, Cserti-Gazdewich C, Tinckam K, Kizhakkedathu JN, West L, Keshavjee S, Withers SG, Cypel M | 2022 | Sci Transl Med | View Ex vivo enzymatic treatment converts blood type A donor lungs into universal blood type lungs | Researchers | Clinical research |
| Preparing small-dose red cell concentrates (RCCs) for neonatal and pediatric transfusions: Impact of RCC volume, storage, and irradiation | Olafson C, William N, Howell A, Beaudin L, Gill B, Clarke G, Stephens S, Lopes-Carvalho D, Lane D, Schubert P, McTaggart K, Acker JP | 2022 | Transfusion | View Preparing small-dose red cell concentrates (RCCs) for neonatal and pediatric transfusions: Impact of RCC volume, storage, and irradiation | Researchers | New or improved product or process |
| Circular of information for the use of human blood components: Hematopoietic Progenitor Cells (HPC), Cord Blood | Stewart T | 2022 | Blood.ca website | View Circular of information for the use of human blood components: Hematopoietic Progenitor Cells (HPC), Cord Blood | Health care providers | Benchmarking and standard setting |
| Epidemiology, diagnosis and management of neonatal thrombosis: a single-center cohort study | Paes B, Chan AKC, Shaik M, Patel D, Bhatt MD | 2022 | Blood Coagul Fibrinolysis | View Epidemiology, diagnosis and management of neonatal thrombosis: a single-center cohort study | Health care providers | Clinical research |
| Sexual risk behavior questions: Understanding and mitigating donor discomfort | Haw J, Woo H, Kohut T, Fisher W | 2022 | Transfusion | View Sexual risk behavior questions: Understanding and mitigating donor discomfort | Blood operators | MSM research |
| Mixing study to diagnose heparin-resistance caused by functional antithrombin deficiency | Bahabri A, Moffat KA, Carlino SA, Chan AKC, Bhatt MD | 2022 | Int J Lab Hematol | View Mixing study to diagnose heparin-resistance caused by functional antithrombin deficiency | Researchers | Basic research |
| Filamin A regulates caspase-3 cleavage in platelets in a protein kinase C (PKC)-dependent manner | De Silva E, Devine DV, Jan E, Roskelley CD, Kim H | 2022 | Biochem J | View Filamin A regulates caspase-3 cleavage in platelets in a protein kinase C (PKC)-dependent manner | Researchers | Basic research |
| Model of Acute Liver Failure in an Isolated Perfused Porcine Liver—Challenges and Lessons Learned | Hefler J, Hatami S, Thiesen A, Olafson C, Durand K, Acker J, Karvellas CJ, Bigam DL, Freed DH, Shapiro AMJ | 2022 | Biomedicines | View Model of Acute Liver Failure in an Isolated Perfused Porcine Liver—Challenges and Lessons Learned | Researchers | New or improved product or process |
| Chapitre 10. Les réactions transfusionnelles | Laureano M, Khandelwal A, Yan M | 2022 | Guide de la pratique transfusionnelle | View Chapitre 10. Les réactions transfusionnelles | Health care providers | Benchmarking and standard setting |
| Coagulation and complement: Key innate defense participants in a seamless web | Pryzdial ELG, Leatherdale A, Conway EM | 2022 | Front Immunol | View Coagulation and complement: Key innate defense participants in a seamless web | Researchers | Basic research |
| ResearchUnit: Evaluating infusion pump safety for red blood cell transfusions | Wolfe A | 2022 | Blood.ca website | View ResearchUnit: Evaluating infusion pump safety for red blood cell transfusions | Researchers | Benchmarking and standard setting |
| The Missing Pieces to the Cold-Stored Platelet Puzzle | Zhao H, Devine DV | 2022 | Int J Mol Sci | View The Missing Pieces to the Cold-Stored Platelet Puzzle | Researchers | Basic research |
| Use of CRISPR/Cas9 gene editing to improve chimeric antigen-receptor T cell therapy: A systematic review and meta-analysis of preclinical studies | Maganti HB, Kirkham AM, Bailey AJM, Shorr R, Kekre N, Pineault N, Allan DS | 2022 | Cytotherapy | View Use of CRISPR/Cas9 gene editing to improve chimeric antigen-receptor T cell therapy: A systematic review and meta-analysis of preclinical studies | Researchers | Clinical research |
| The international experience of bacterial screen testing of platelet components with automated microbial detection systems: An update | Kamel H, Ramirez-Arcos S, McDonald C, ISBT Transfusion-Transmitted Infectious Disease Bacterial Working Party Bacterial Subgroup | 2022 | Vox Sang | View The international experience of bacterial screen testing of platelet components with automated microbial detection systems: An update | Researchers | Benchmarking and standard setting |
| Vaccine-induced immune thrombotic thrombocytopenia (VITT): Update on diagnosis and management considering different resources | Greinacher A, Langer F, Makris M, Pai M, Pavord S, Tran H, Warkentin TE | 2022 | J Thromb Haemost | View Vaccine-induced immune thrombotic thrombocytopenia (VITT): Update on diagnosis and management considering different resources | Health care providers | Clinical research |
| Cytomegalovirus Seropositivity in Older Adults Changes the T Cell Repertoire but Does Not Prevent Antibody or Cellular Responses to SARS-CoV-2 Vaccination | Breznik JA, Huynh A, Zhang A, Bilaver L, Bhakta H, Stacey HD, Ang JC, Bramson JL, Nazy I, Miller MS, Denburg J, Costa AP, Bowdish DME | 2022 | J Immunol | View Cytomegalovirus Seropositivity in Older Adults Changes the T Cell Repertoire but Does Not Prevent Antibody or Cellular Responses to SARS-CoV-2 Vaccination | Health care providers | Clinical research |
| THP-1 cells transduced with CD16A utilize Fcγ receptor I and III in the phagocytosis of IgG-sensitized human erythrocytes and platelets | Gil Gonzalez L, Fernandez-Marrero Y, Norris PAA, Tawhidi Z, Shan Y, Cruz-Leal Y, Won KD, Frias-Boligan K, Branch DR, Lazarus AH | 2022 | PLoS One | View THP-1 cells transduced with CD16A utilize Fcγ receptor I and III in the phagocytosis of IgG-sensitized human erythrocytes and platelets | Researchers | Basic research |
| ABO O blood group as a risk factor for platelet reactivity in heparin-induced thrombocytopenia | Karnes JH, Rollin J, Giles JB, Martinez KL, Steiner HE, Shaffer CM, Momozawa Y, Inai C, Bombin A, Shi M, Mosley JD, Stanaway I, Selleng K, Thiele T, Mushiroda T, Pouplard C, Heddle NM, Kubo M, Phillips EJ, Warkentin TE, Gruel Y, Greinacher A, Roden DM | 2022 | Blood | View ABO O blood group as a risk factor for platelet reactivity in heparin-induced thrombocytopenia | Researchers | Basic research |
| HIV incidence and related risks among gay, bisexual, and other men who have sex with men in Montreal, Toronto, and Vancouver: Informing blood donor selection criteria in Canada | Lambert G, Cox J, Fourmigue A, Dvorakova M, Apelian H, Moodie EEM, Grace D, Skakoon-Sparling S, Moore DM, Lachowsky N, Jollimore J, Lal A, Parlette A, Hart TA | 2022 | Transfusion | View HIV incidence and related risks among gay, bisexual, and other men who have sex with men in Montreal, Toronto, and Vancouver: Informing blood donor selection criteria in Canada | Researchers | MSM research |
| Chapter 5. Concentrates for hemostatic disorders and hereditary angioedema | Poon MC, Goodyear D, Rydz N, Lee A | 2022 | Clinical Guide to Transfusion | View Chapter 5. Concentrates for hemostatic disorders and hereditary angioedema | Health care providers | Benchmarking and standard setting |
| Retention of hemostatic and immunological properties of frozen plasma and COVID-19 convalescent apheresis fresh-frozen plasma produced and freeze-dried in Canada | Sheffield WP, Bhakta V, Howell A, Jenkins C, Serrano K, Johnson N, Lin Y-CJ, Colwill K, Rathod B, Greenberg B, Gingras A-C, Evans DH, Flaumenhaft E, Beckett A, Drews SJ, Devine DV | 2022 | Transfusion | View Retention of hemostatic and immunological properties of frozen plasma and COVID-19 convalescent apheresis fresh-frozen plasma produced and freeze-dried in Canada | Researchers | Basic research |
| Multicenter evaluation of the IL-3-pSTAT5 assay to assess the potency of cryopreserved stem cells from cord blood units: The BEST Collaborative study | Trépanier P, Fournier D, Simard C, Fontaine MJ, Stroncek D, Takanashi M, McKenna D, Schwartz J, Tanhehco YC, Reems J-A, Torrents S, Kogler G, Liedtke S, Giroux M, Holovati JL, Louis I, Prasath A, Pineault N, Bazin R, The Biomedical Excellence for Safer Transfusion Collaborative | 2022 | Transfusion | View Multicenter evaluation of the IL-3-pSTAT5 assay to assess the potency of cryopreserved stem cells from cord blood units: The BEST Collaborative study | Researchers | Benchmarking and standard setting |
| Comparison of Neutrophil Function in Granulocyte Concentrates From Prednisone- and G-CSF-Treated Donors: Effect of Stimulant, Leukapheresis and Storage | Murru A, Allard M-È, Paré G, Vaillancourt M, Boyer L, Cayer M-P, Vitry J, Landry P, Labrecque M-M, Robitaille N, Branch DR, Girard M, Fernandes MJ | 2022 | Front Med | View Comparison of Neutrophil Function in Granulocyte Concentrates From Prednisone- and G-CSF-Treated Donors: Effect of Stimulant, Leukapheresis and Storage | Researchers | Basic research |
| Comparative 6-Month Wild-Type and Delta-Variant Antibody Levels and Surrogate Neutralization for Adults Vaccinated with BNT162b2 versus mRNA-1273 | Grunau B, Golding L, Prusinkiewicz MA, Asamoah-Boaheng M, Armour R, Marquez AC, Jassem AN, Barakauskas V, O’Brien SF, Drews SJ, Haig S, Lavoie PM, Goldfarb DM | 2022 | Microbiol Spectr | View Comparative 6-Month Wild-Type and Delta-Variant Antibody Levels and Surrogate Neutralization for Adults Vaccinated with BNT162b2 versus mRNA-1273 | Researchers | Clinical research |
| The impact of donor ferritin testing on blood availability in Canada | Blake JT, O'Brien SF, Goldman M | 2022 | Vox Sang | View The impact of donor ferritin testing on blood availability in Canada | Blood operators | New or improved product or process |
| Preservation and Storage of Cells for Therapy: Current Applications and Protocols | Acker JP, Bondarovych M, Brunotte R, Buriak IA, Fuller BJ, Glasmacher B, Goltsev AM, Gregor J, Gryshkov O, Herrity K, Honegrová B, Hunt CJ, Jandová M, Johnstone BH, Kilbride P, Lánská M, Mann J, Měřička P, Musall KG, Mutsenko V, Mykhailova O, Petrenko Y, Radocha J, Sherry AM, Stacey GN, Štěrba L, Vokurková D, William N, Woods EJ | 2022 | Cell Engineering and Regeneration | View Preservation and Storage of Cells for Therapy: Current Applications and Protocols | Researchers | Benchmarking and standard setting |
| FAQ: Donor high titre isohemagglutinin (anti-A/anti-B) testing at Canadian Blood Services | Bodnar M, Bienz M, Clarke G | 2022 | Blood.ca website | View FAQ: Donor high titre isohemagglutinin (anti-A/anti-B) testing at Canadian Blood Services | Health care providers | New or improved product or process |
| International guidelines regarding the role of IVIG in the management of Rh- and ABO-mediated haemolytic disease of the newborn | Lieberman L, Lopriore E, Baker JM, Bercovitz RS, Christensen RD, Crighton G, Delaney M, Goel R, Hendrickson JE, Keir A, Landry D, La Rocca U, Lemyre B, Maier RF, Muniz-Diaz E, Nahirniak S, New HV, Pavenski K, Dos Santos MCP, Ramsey G, Shehata N, International Collaboration for Transfusion Medicine Guidelines | 2022 | Brit J Haem | View International guidelines regarding the role of IVIG in the management of Rh- and ABO-mediated haemolytic disease of the newborn | Health care providers | Benchmarking and standard setting |
| The response of a human haematopoietic cell line to trehalose-loaded liposomes and their effect on post-thaw membrane integrity | Scott KL, William N, Acker JP | 2022 | Cryobiology | View The response of a human haematopoietic cell line to trehalose-loaded liposomes and their effect on post-thaw membrane integrity | Researchers | Basic research |
| Circulaire d'information utilisation de composants sanguins humains: Plaquettes | Stewart T | 2022 | Blood.ca website | View Circulaire d'information utilisation de composants sanguins humains: Plaquettes | Health care providers | Benchmarking and standard setting |
| Cost-effectiveness of noninvasive fetal RhD blood group genotyping in nonalloimmunized and alloimmunized pregnancies | Gajic-Veljanoski O, Li C, Schaink AK, Guo J, Shehata N, Charames GS, de Vrijer B, Clarke G, Pechlivanoglou P, Okun N, Kandel R, Dooley J, Higgins C, Ng V, Sikich N | 2022 | Transfusion | View Cost-effectiveness of noninvasive fetal RhD blood group genotyping in nonalloimmunized and alloimmunized pregnancies | Researchers | Clinical research |
| HIV residual risk in Canada for apheresis source plasma donation without deferral for men who have sex with men | Aubé E, Lewin A, O'Brien SF, Grégoire Y, Pillonel J, Steele WR, Custer B, Davison KL, Germain M, Seed CR, Camirand Lemyre F, the Surveillance RA, Policy Subgroup of the ISBT Transfusion Transmitted Infectious Diseases Working Party | 2022 | Vox Sang | View HIV residual risk in Canada for apheresis source plasma donation without deferral for men who have sex with men | Blood operators | MSM research |
| The Relationship Between Anti-Spike SARS-CoV-2 Antibody Levels and Risk of Breakthrough COVID-19 Among Fully Vaccinated Adults | Asamoah-Boaheng M, Goldfarb DM, Karim ME, O’Brien SF, Wall N, Drews SJ, Barakauskas V, Jassem AN, Grunau B | 2022 | J Infect Dis | View The Relationship Between Anti-Spike SARS-CoV-2 Antibody Levels and Risk of Breakthrough COVID-19 Among Fully Vaccinated Adults | Researchers | Clinical research |
| Development and internal validation of a clinical prediction model for the diagnosis of immune thrombocytopenia | Li N, Mahamad S, Parpia S, Iorio A, Foroutan F, Heddle NM, Hsia CC, Sholzberg M, Rimmer E, Shivakumar S, Sun HL, Refaei M, Hamm C, Arnold DM | 2022 | J Thromb Haemost | View Development and internal validation of a clinical prediction model for the diagnosis of immune thrombocytopenia | Researchers | New or improved product or process |
| Surveillance report | O'Brien SF | 2022 | Blood.ca website | View Surveillance report | Blood operators | Benchmarking and standard setting |
| Immunospecific analysis of in vitro and ex vivo surface-immobilized protein complex | Sask KN, Thong B, Goodarzynejad N, Berry LR, Chan AKC | 2022 | Biointerphases | View Immunospecific analysis of in vitro and ex vivo surface-immobilized protein complex | Researchers | Basic research |
| GRADE Guidance 34: update on rating imprecision using a minimally contextualized approach | Zeng L, Brignardello-Petersen R, Hultcrantz M, Mustafa RA, Murad MH, Iorio A, Traversy G, Akl EA, Mayer M, Schünemann HJ, Guyatt GH | 2022 | J Clin Epidemiol | View GRADE Guidance 34: update on rating imprecision using a minimally contextualized approach | Researchers | Clinical research |
| Recognizing Vaccine-Induced Immune Thrombotic Thrombocytopenia | Iba T, Levy JH, Warkentin TE | 2022 | Crit Care Med | View Recognizing Vaccine-Induced Immune Thrombotic Thrombocytopenia | Health care providers | Benchmarking and standard setting |
| A scalable serology solution for profiling humoral immune responses to SARS-CoV-2 infection and vaccination | Colwill K, Galipeau Y, Stuible M, Gervais C, Arnold C, Rathod B, Abe KT, Wang JH, Pasculescu A, Maltseva M, Rocheleau L, Pelchat M, Fazel-Zarandi M, Iskilova M, Barrios-Rodiles M, Bennett L, Yau K, Cholette F, Mesa C, Li AX, Paterson A, Hladunewich MA, Goodwin PJ, Wrana JL, Drews SJ, Mubareka S, McGeer AJ, Kim J, Langlois M-A, Gingras A-C, Durocher Y | 2022 | medRxiv | View A scalable serology solution for profiling humoral immune responses to SARS-CoV-2 infection and vaccination | Researchers | New or improved product or process |