Our Research Publications

Updated November 2023

Title Authors Year Journal Link to Article Intended Audience Purpose
Thymic stromal lymphopoietin induces platelet mitophagy and promotes thrombosis in Kawasaki disease Fu L, MacKeigan DT, Gong Q, Che D, Xu Y, Pi L, Sun C, Yu H, Chen K, Zhou H, Jiang Z, Wang Z, Zhang L, Cerenzia EG, Ni H, Gu X 2023 Brit J Haem View Researchers Clinical research
Blood donor eligibility criteria for medical conditions: A BEST collaborative study Jacquot C, Tiberghien P, van den Hurk K, Ziman A, Shaz B, Apelseth TO, Goldman M, The Biomedical Excellence for Safer Transfusion Collaborative 2022 Vox Sang View Researchers Benchmarking and standard setting
SARS-CoV-2 Seroprevalence among Canadian Blood Donors: The Advance of Omicron O’Brien SF, Caffrey N, Yi Q-L, Pambrun C, Drews SJ 2022 Viruses View Researchers Clinical research
Prevalence of selected bleeding and thrombotic events in persons with hemophilia versus the general population: A scoping review Shapiro AD, Hardesty BM, Peyvandi F, Iorio A 2023 Res Pract Thromb Haemost View Researchers Clinical research
Animal model of fetal and neonatal immune thrombocytopenia: role of neonatal Fc receptor in the pathogenesis and therapy Chen P, Li C, Lang S, Zhu G, Reheman A, Spring CM, Freedman J, Ni H 2010 Blood View Researchers Basic research
Comparison of detection methods for cell surface globotriaosylceramide Kim M, Binnington B, Sakac D, Fernandes KR, Shi SP, Lingwood CA, Branch DR 2011 J Immunol Methods View Researchers Basic research
Defining Significant Events for Neonatal and Pediatric Transport: Results of a Combined Delphi and Consensus Meeting Process Gunz A, McNally J, Whyte H, O'Hearn K, Foster J, Parker M, Dhanani S 2016 J Pediatr Intensive Care View Researchers Clinical research
Differential Expression Analysis by RNA-Seq Reveals Perturbations in the Platelet mRNA Transcriptome Triggered by Pathogen Reduction Systems Osman A, Hitzler WE, Ameur A, Provost P 2015 PLoS One View Researchers Basic research
Effect of platelet additive solution on bacterial dynamics and their influence on platelet quality in stored platelet concentrates Greco CA, Zhang JG, Kalab M, Yi Q-L, Ramirez-Arcos SM, Gyongyossy-Issa MIC 2010 Transfusion View Researchers Basic research
E-selectin mediated adhesion and migration of endothelial colony forming cells is enhanced by SDF-1alpha/CXCR4 Sun J, Li Y, Graziani GM, Filion L, Allan DS 2013 PLoS One View Researchers Basic research
Extracellular vesicles in transfusion-related immunomodulation and the role of blood component manufacturing Almizraq RJ, Seghatchian J, Acker JP 2016 Transfusion and Apheresis Science View Researchers Basic research
Human bone marrow mesenchymal stromal cell-derived osteoblasts promote the expansion of hematopoietic progenitors through Beta-catenin and Notch signaling pathways Michalicka M, Boisjoli G, Jahan S, Hovey O, Doxtator E, Abu-Khader A, Pasha R, Pineault N 2017 Stem Cells Dev View Researchers Basic research
Mice with deleted multimerin 1 and ?-synuclein genes have impaired platelet adhesion and impaired thrombus formation that is corrected by multimerin 1 Reheman A, Tasneem S, Ni H, Hayward CPM 2010 Thromb Res View Researchers Basic research
Mouse background and IVIG dosage are critical in establishing the role of inhibitory Fcgamma receptor for the amelioration of experimental ITP Leontyev D, Katsman Y, Branch DR 2012 Blood View Researchers Basic research
Physical characterization of hematopoietic stem cells using multidirectional label-free light scatterings Shahin H, Gupta M, Janowska-Wieczorek A, Rozmus W, Tsui YY 2016 Optics Express View Researchers Basic research
Red blood cell replacement, or nanobiotherapeutics with enhanced red blood cell functions? Chang TMS 2015 Artif Cells Nanomed Biotechnol View Researchers Basic research
Self-Assembly of a Functional Triple Protein: Hemoglobin-Avidin-Hemoglobin via Biotin–Avidin Interactions Singh S, Kluger R 2016 Biochemistry View Researchers Basic research
The effect of grafted methoxypoly(ethylene glycol) chain length on the inhibition of respiratory syncytial virus (RSV) infection and proliferation Sutton TC, Scott MD 2010 Biomaterials View Researchers Basic research
The nonhemostatic immune functions of platelets Kapur R, Semple JW 2016 Semin Hematol View Researchers Basic research
Test-retest properties of the Patient Reported Outcomes, Burdens and Experiences (PROBE) questionnaire and its constituent domains Chai-Adisaksopha C, Skinner MW, Curtis R, Frick N, Nichol MB, Noone D, O'Mahony B, Page D, Stonebraker J, Thabane L, Crowther MA, Iorio A 2019 Haemophilia View Researchers Clinical research
Cellular immune responses to platelet factor 4 and heparin complexes in patients with heparin-induced thrombocytopenia Nazy I, Clare R, Staibano P, Warkentin TE, Larché M, Moore JC, Smith JW, Whitlock RP, Kelton JG, Arnold DM 2018 J Thromb Haemost View Researchers Clinical research
Modulating Intracellular Ice Growth with Cell-Permeating Small-Molecule Ice Recrystallization Inhibitors Poisson JS, Acker JP, Briard JG, Meyer JE, Ben RN 2018 Langmuir View Researchers Basic research
The Monocyte Monolayer Assay: Past, Present and Future Tong TN, Cen S, Branch DR 2018 Transfus Med Rev View Researchers Basic research
Corrigendum to "Comparison of mammalian and bacterial expression library screening to detect recombinant alpha-1 proteinase inhibitor variants with enhanced thrombin inhibitory capacity" [J. Biotechnol. 208 (2015) 54-62] Gierczak RF, Bhakta V, Xie M, Sheffield WP 2020 J Biotechnol View Researchers Basic research
Modulating Intracellular Ice Growth with Cell-Permeating Small-Molecule Ice Recrystallization Inhibitors Poisson JS, Acker JP, Briard JG, Meyer JE, Ben RN 2019 Langmuir View Researchers Basic research
Using pharmacokinetics for tailoring prophylaxis in people with hemophilia switching between clotting factor products: A scoping review Yu JK, Iorio A, Edginton AN, Wapps co?investigators 2019 Res Pract Thromb Haemost View Researchers Clinical research
The Effect of Age and Type of Media on Growth Kinetics of Human Amniotic Fluid Stem cells Borzou B, Mehrabani D, Zare S, Zamani-Pereshkaft M, Acker JP 2020 Biopreserv Biobank View Researchers Basic research
HIT: still stringing us along Warkentin TE 2020 Blood View Researchers Clinical research
Thrombospondin-1/CD47 signaling modulates transmembrane cation conductance, survival, and deformability of human red blood cells Bissinger R, Petkova-Kirova P, Mykhailova O, Oldenborg P-A, Novikova E, Donkor DA, Dietz T, Bhuyan AAM, Sheffield WP, Grau M, Artunc F, Kaestner L, Acker JP, Qadri SM 2020 Cell Signal View Researchers Basic research
Successful prenatal therapy for anti-CD36-mediated severe FNAIT by deglycosylated antibodies in a novel murine model Xu X, Chen D, Ye X, Xia W, Xu Y, Chen Y, Shao Y, Deng J, Ding H, Liu J, Wang J, Ni H, Fu Y, Santoso S 2021 Blood View Researchers Basic research
From demand forecasting to inventory ordering decisions for red blood cells through integrating machine learning, statistical modeling, and inventory optimization Li N, Arnold DM, Down DG, Barty R, Blake J, Chiang F, Courtney T, Waito M, Trifunov R, Heddle NM 2022 Transfusion View Researchers New or improved product or process
The authors reply Iba T, Levy JH, Warkentin TE 2022 Crit Care Med View Researchers Clinical research
SARS-CoV-2 seroprevalence among Vancouver public school staff in British Columbia, Canada Goldfarb DM, Mâsse LC, Watts AW, Hutchison SM, Muttucomaroe L, Bosman ES, Barakauskas VE, Choi A, Irvine MA, Reicherz F, Coombs D, O’Reilly C, Sediqi S, Razzaghian HR, Sadarangani M, O’Brien SF, Lavoie PM 2021 medRxiv View Researchers Clinical research
A scalable serology solution for profiling humoral immune responses to SARS-CoV-2 infection and vaccination Colwill K, Galipeau Y, Stuible M, Gervais C, Arnold C, Rathod B, Abe KT, Wang JH, Pasculescu A, Maltseva M, Rocheleau L, Pelchat M, Fazel-Zarandi M, Iskilova M, Barrios-Rodiles M, Bennett L, Yau K, Cholette F, Mesa C, Li AX, Paterson A, Hladunewich MA, Goodwin PJ, Wrana JL, Drews SJ, Mubareka S, McGeer AJ, Kim J, Langlois M-A, Gingras A-C, Durocher Y 2022 Clin Transl Immunol View Researchers New or improved product or process
SARS-CoV-2 spike-dependent platelet activation in COVID-19 vaccine-induced thrombocytopenia Appelbaum J, Arnold DM, Kelton JG, Gernsheimer T, Jevtic SD, Ivetic N, Smith JW, Nazy I 2022 Blood Adv View Researchers Basic research
A Higher Antibody Response Is Generated With a 6- to 7-Week (vs Standard) Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Vaccine Dosing Interval Grunau B, Asamoah-Boaheng M, Lavoie PM, Karim ME, Kirkham TL, Demers PA, Barakauskas V, Marquez AC, Jassem AN, O’Brien SF, Drews SJ, Haig S, Cheskes S, Goldfarb DM 2021 Clin Infect Dis View Researchers Clinical research
A flow cytometric method for platelet counting in platelet concentrates van der Meer PF, Karssing-van Leeuwen W, Kurtz J, Spengler H-P, Blair A, Devine D, Harrison P, Lambrecht B, VandenBroeke T, de Wildt J, de Korte D, on behalf of the Biomedical Excellence for Safer Transfusion C 2012 Transfusion View Researchers New or improved product or process
A trial to determine whether septic shock-reversal is quicker in pediatric patients randomized to an early goal-directed fluid-sparing strategy versus usual care (SQUEEZE): study protocol for a pilot randomized controlled trial Parker MJ, Thabane L, Fox-Robichaud A, Liaw P, Choong K 2016 Trials View Researchers Clinical research
Alpha-1 Acid Glycoprotein Reduces Hepatic Leukocyte Recruitment in Murine Models of Either Early Endotoxemia or Early Sepsis McCurdy TR, Patrick AL, Eltringham-Smith LJ, Bhakta V, Sheffield WP, Fox-Robichaud AE 2014 Microcirculation View Researchers Basic research
Antigens protected functional red blood cells by the membrane grafting of compact hyperbranched polyglycerols Chapanian R, Constantinescu I, Brooks DE, Scott MD, Kizhakkedathu J 2013 J Vis Exp View Researchers Basic research
Buffy coat (top/bottom)- and whole-blood filtration (top/top)-produced red cell concentrates differ in size of extracellular vesicles Bicalho B, Pereira AS, Acker JP 2015 Vox Sang View Researchers Basic research
Cholesterol efflux in megakaryocyte progenitors suppresses platelet production and thrombocytosis Murphy AJ, Bijl N, Yvan-Charvet L, Welch CB, Bhagwat N, Reheman A, Wang Y, Shaw JA, Levine RL, Ni H, Tall AR, Wang N 2013 Nat Med View Researchers Basic research
Concentré de recherche: La sécrétion de cellules immunitaires peut protéger les patients contre le syndrome respiratoire post-transfusionnel Semple J 2017 Blood.ca website View Researchers Basic research
Design, implementation, and evaluation of a knowledge translation intervention to increase organ donation after cardiocirculatory death in Canada: a study protocol Squires JE, Grimshaw JM, Taljaard M, Linklater S, Chasse M, Shemie SD, Knoll GA 2014 Implement Sci View Researchers Other
Efficiency of riboflavin and ultraviolet light treatment against high levels of biofilm?derived Staphylococcus epidermidis in buffy coat platelet concentrates Taha M, Culibrk B, Kalab M, Schubert P, Yi QL, Goodrich R, Ramirez?Arcos S 2017 Vox Sang View Researchers New or improved product or process
Evaluation of CONSORT compliance in TRANSFUSION Jaffer AM, Wang G, Barty RL, Shih AW 2015 Transfusion View Researchers Other
Hematopoietic Stem Cell Mobilization and Homing after Transplantation: The Role of MMP-2, MMP-9, and MT1-MMP Shirvaikar N, Marquez-Curtis LA, Janowska-Wieczorek A 2012 Biochem Res Int View Researchers Basic research
IgG-Mediated Immune Suppression to Erythrocytes by Polyclonal Antibodies Can Occur in the Absence of Activating or Inhibitory Fc? Receptors in a Full Mouse Model Bernardo L, Yu H, Amash A, Zimring JC, Lazarus AH 2015 J Immunol View Researchers Basic research
In silico analysis suggests repurposing of ibuprofen for prevention and treatment of EBOLA virus disease Veljkovic V, Goeijenbier M, Glisic S, Veljkovic N, Perovic VR, Sencanski M, Branch DR, Paessler S 2015 F1000Res View Researchers Basic research
Involvement of the contact phase and intrinsic pathway in herpes simplex virus-initiated plasma coagulation Gershom ES, Sutherland MR, Lollar P, Pryzdial EL 2010 J Thromb Haemost View Researchers Basic research