Our Research Publications

Updated August 2025

Title Authors Year Journal Link to Article Intended Audience Purpose
Correction of haemorrhagic shock-associated coagulopathy and impaired haemostasis by plasma, prothrombin complex concentrates or an activated protein C-targeted DNA aptamer in mice Eltringham-Smith LJ, Meixner SC, Pryzdial ELG, Sheffield WP 2023 Sci Rep View Researchers Basic research
Engineered Compounds to Control Ice Nucleation and Recrystallization William N, Mangan S, Ben RN, Acker JP 2023 Ann Rev Biomed Eng View Researchers New or improved product or process
The under-appreciated world of the serpin family of serine proteinase inhibitors Bouton M-C, Geiger M, Sheffield WP, Irving JA, Lomas DA, Song S, Satyanarayanan RS, Zhang L, McFadden G, Lucas AR 2023 EMBO Mol Med View Researchers Basic research
Diminished Neutralization Capacity of SARS-CoV-2 Omicron BA.1 in Donor Plasma Collected from January to March 2021 Lin Y-CJ, Evans DH, Robbins NF, Orjuela G, Abe KT, Rathod B, Colwill K, Gingras A-C, Tuite A, Yi Q-L, O’Brien SF, Drews SJ 2023 Microbiol Spectr View Researchers Clinical research
Risk of variant Creutzfeldt–Jakob disease in a simulated cohort of Canadian blood donors Pozzo di Borgo A, Germain M, O'Brien SF, Delage G, Renaud C, Lewin A 2023 Vox Sang View Researchers Clinical research
Transfusion camp: A retrospective study of self-reported impact on postgraduate trainee transfusion practice Yeung KCY, Kapitany C, Chargé S, Callum J, Cserti-Gazdewich C, D'Empaire PP, Khandelwal A, Lieberman L, Lee C, Pavenski K, Pendergrast J, Shehata N, Hsia CC, Lavoie M, Murphy MF, Prokopchuk-Gauk O, Rahmani M, Trudeau J, Zeller MP, Lin Y 2023 Transfusion View Health care providers Education research
B cells and antibodies in refractory immune thrombocytopenia Roeser A, Lazarus AH, Mahévas M 2023 Br J Haematol View Researchers Benchmarking and standard setting
Cultured CD71+ erythroid cells modulate the host immune response Alshalani A, Beuger BM, van Bruggen R, Acker JP, Juffermans NP 2023 Transfus Med View Researchers Basic research
Importance du fer chez les donneurs de sang total : la perspective canadienne Khandelwal A, Pambrun C, Goldman M 2023 Blood.ca website View Health care providers Benchmarking and standard setting
The Effect of the COVID-19 Pandemic on Unrelated Allogeneic Hematopoietic Donor Collections and Safety Parmar G, Allan DS, Morris G, Dibdin N, Ganz K, Mostert K, Paulson K, Petraszko T, Stevens N, Seftel MD 2023 Curr Oncol View Health care providers Clinical research
Antigen copy number and antibody dose can determine the outcome of erythrocyte alloimmunization inducing either antibody-mediated immune suppression or enhancement in a murine model Wabnitz H, Cruz-Leal Y, Lazarus AH 2023 Transfusion View Researchers Basic research
La maladie hémolytique du nouveau-né (incompatibilité ABO) International Collaboration for Transfusion Medicine Guidelines 2023 ICTMG.org View General public Other
Desialylated Platelet Clearance in the Liver is a Novel Mechanism of Systemic Immunosuppression Li J, Karakas D, Xue F, Chen Y, Zhu G, Yucel YH, MacParland SA, Zhang H, Semple JW, Freedman J, Shi Q, Ni H 2023 Research View Researchers Basic research
Transfusion Camp Rwanda: A prospective feasibility study evaluating the delivery of Transfusion Camp to a multidisciplinary group of postgraduate medical trainees in Rwanda Hagumimana J, Skelton T, Pendergrast J, Nizeyimana F, Masaisa F, Kanyamuhunga A, Gashaija C, Chargé S, Kapitany C, Morgan M, Meirovich H, Lin Y 2023 Transfusion View Health care providers Education research
Willingness and eligibility to donate blood under 12-month and 3-month deferral policies among gay, bisexual, and other men who have sex with men in Ontario, Canada Brennan D, Armstrong JP, Kesler M, Bekele T, Lachowksy N, Grace D, Hart TA, Souleymanov R, Adam B 2023 PLOS Glob Public Health View Researchers MSM research
BAY 81-8973 Efficacy and Safety in Previously Untreated and Minimally Treated Children with Severe Hemophilia A: The LEOPOLD Kids Trial Ljung R, Chan AKC, Glosli H, Afonja O, Becker B, Tseneklidou-Stoeter D, Mancuso ME, Saulyte-Trakymiene S, Kenet G 2023 Thromb Haemost View Researchers Clinical research
A multiphasic approach to solve misidentification of Cutibacterium acnes as Atopobium vaginae during routine bacterial screening of platelet concentrates using the VITEK 2 system Kumaran D, Laflamme C, Ramirez-Arcos S 2023 Access Microbiol View Researchers Benchmarking and standard setting
Long-term preservation of red blood cells through deep supercooling Isiksacan Z, William N, Yarmush ML, Acker JP, Usta OB 2023 Cryobiology View Researchers Basic research
Monitoring viral genomic sequences in transfusion-transmitted viruses Candotti D, Drews SJ, Faddy HM, ISBT Transfusion-Transmitted Infectious Diseases Working Party SoV 2023 Vox Sang View Blood operators Clinical research
Do Children With an Allergic Transfusion Reaction Require Premedication or All Blood Products? Bahabri A, Barty R, Li N, Liu Y, Kovalova T, Chan AKC 2023 J Pediatr Hematol Oncol View Health care providers Clinical research
How do we forecast tomorrow's transfusion? Applying social science approaches to meet tomorrow's transfusion needs: Blood donors and donation Haw J, Holloway K, Goldman M 2023 Transfus Clin Biol View Researchers Ethical, legal & social implications research
The high prevalence of occult hepatitis B infections among the partners of chronically infected HBV blood donors emphasizes the potential residual risk to blood safety Ye X, Li T, Yu B, Zeng J, Shi Y, Xie H, Branch DR, Loriamini M, Li B, Chen L 2023 J Med Virol View Blood operators Clinical research
HIV Pre-Exposure Prophylaxis, Blood Donor Deferral, Occult Infection, and Risk of HIV Transmission by Transfusion: A Fine Balance Between Evidence-Based Donor Selection Criteria and Transfusion Safety Leblanc J-F, Custer B, Van de Laar T, Drews SJ, Germain M, Lewin A 2023 Transfus Med Rev View Researchers Clinical research
Hepatitis B virus genotype surveillance in Canadian blood donors and a referred patient population, 2016–2021 Osiowy C, Giles E, Lowe CF, Matic N, Murphy DG, Uzicanin S, Drews SJ, O'Brien SF 2023 Vox Sang View Researchers Epidemiology research
Determining the Optimal SARS-CoV-2 mRNA Vaccine Dosing Interval for Maximum Immunogenicity Asamoah-Boaheng M, Goldfarb D, Prusinkiewicz MA, Golding L, Karim ME, Barakauskas V, Wall N, Jassem AN, Marquez AC, MacDonald C, O'Brien SF, Lavoie P, Grunau B 2023 Cureus View Researchers Clinical research
Staphylococcal Enterotoxins Enhance Biofilm Formation by Staphylococcus aureus in Platelet Concentrates Chi SI, Ramirez-Arcos S 2023 Microorganisms View Researchers Basic research
‘A Most Equitable Drug’: How the Clinical Studies of Convalescent Plasma as a Treatment for SARS-CoV-2 Might Usefully Inform Post-Pandemic Public Sector Approaches to Drug Development Grundy Q, Campbell C, Ali R, Herder M, Holloway K 2023 J Law Med Ethics View Researchers Ethical, legal & social implications research
Massive Hemorrhage Protocol: A Practical Approach to the Bleeding Trauma Patient Petrosoniak A, Pavenski K, da Luz LT, Callum J 2023 Emerg Med Clin North Am View Health care providers Benchmarking and standard setting
Severe fetal anemia caused by anti-Jra: Burst forming unit-erythroid colony formation inhibition assay suggesting possible erythroid suppression mechanism Tran A, Yan MTS, Branch DR, Blacquiere M, Pineault N, Pasha R, Clarke G 2023 Transfusion View Researchers Clinical research
Serum from half of patients with immune thrombocytopenia triggers macrophage phagocytosis of platelets Norris PAA, Tawhidi Z, Sachs UJ, Cserti-Gazdewich CM, Lin Y, Callum J, Gil Gonzalez L, Shan Y, Branch DR, Lazarus AH 2023 Blood Adv View Researchers Basic research
Solvent detergent (S/D) treated plasma (Octaplasma) Ning S, Blais-Normandin I, Tordon B, Mack J, Webert K 2023 Blood.ca website View Health care providers Benchmarking and standard setting
Enfermedad hemolítica del recién nacido (HDN): enfermedad de Rhesus (Rh) y otros anticuerpos no-ABO International Collaboration for Transfusion Medicine Guidelines 2023 ICTMG.org View General public Other
Quality assessment of red blood cell concentrates from blood donors at the extremes of the age spectrum: The BEST collaborative study Cloutier M, Cognasse F, Yokoyama APH, Hazegh K, Mykhailova O, Brandon-Coatham M, Hamzeh-Cognasse H, Kutner JM, Acker JP, Kanias T, the Biomedical Excellence for Safer Transfusion Collaborative 2023 Transfusion View Researchers Benchmarking and standard setting
Taking lessons from nature to improve cell therapy cryopreservation Acker J, William N, Coatham M 2023 Cell Gene Ther Insights View Researchers Basic research
Molecular Screening of Blood Donors for Babesia in Tyrol, Austria Bloch EM, Siller A, Tonnetti L, Drews SJ, Spencer BR, Hedges D, Mergenthal T, Weber-Schehl M, Astl M, Patel EU, Gaber M, Schennach H 2023 Transfus Med Hemother View Researchers Clinical research
Characteristics of VITT antibodies in patients vaccinated with Ad26.COV2.S Huynh A, Arnold DM, Michael JV, Clare R, Smith JW, Daka M, Ianosi-Irimie M, McKenzie SE, Kelton JG, Nazy I 2023 Blood Adv View Researchers Clinical research
Donor sex, pre-donation hemoglobin, and manufacturing affect CD71+ cells in red cell concentrates Li W, William N, Acker JP 2023 Transfusion View Researchers Basic research
Hemocompatibility of bCyclodextrin-Modified (Methacryloyloxy)ethyl Phosphorylcholine Coated Magnetic Nanoparticles Li S, Sharaf MG, Rowe EM, Serrano K, Devine DV, Unsworth LD 2023 Biomolecules View Researchers Basic research
Q&A: Anemia in Hospitalized Patients Siegal D, Callum J, Sztainert T 2023 Blood.ca website View Health care providers Clinical research
Comparing two extracellular additives to facilitate extended storage of red blood cells in a supercooled state William N, Isiksacan Z, Mykhailova O, Olafson C, Yarmush ML, Usta OB, Acker JP 2023 Front Physiol View Researchers Basic research
Evaluating the inventory impact of utilizing low titer platelets in regional hospitals Blake JT, Clarke G, Bodnar M, Stepien J 2023 Transfusion View Blood operators Benchmarking and standard setting
Clinical Outcomes of Umbilical Cord Blood Transplantation Using Ex Vivo Expansion: A Systematic Review and Meta-Analysis of Controlled Studies Saiyin T, Kirkham AM, Bailey AJM, Shorr R, Pineault N, Maganti HB, Allan DS 2023 Transplant Cell Ther View Researchers Clinical research
FAQ: Information for health professionals on apheresis platelet psoralen-treated (APPT) and untreated apheresis platelet in PAS-E Ning S, Nowry A, Zeller M 2023 Blood.ca website View Health care providers Benchmarking and standard setting
Transfusion-transmitted Babesia spp.: a changing landscape of epidemiology, regulation, and risk mitigation Drews SJ, Kjemtrup AM, Krause PJ, Lambert G, Leiby DA, Lewin A, O'Brien SF, Renaud C, Tonnetti L, Bloch EM 2023 J Clin Microbiol View Researchers Benchmarking and standard setting
Lessons learned from the CONCOR-1 trial Callum J, Bégin P, Jamula E, Liu Y, Kron AT, Auclair MC, Cushing M, Arnold DM 2023 Transfus Med View Researchers Clinical research
Validation Plan for Lower Volume Blood tubes Siegal D, Callum J, Sztainert T 2023 Blood.ca website View Health care providers Benchmarking and standard setting
Malattia emolitica del neonato (HDN): malattia di Rhesus (Rh) e MEN da altri anticorpi non-ABO International Collaboration for Transfusion Medicine Guidelines 2023 ICTMG.org View General public Other
Desialylated Platelet Clearance in the Liver is a Novel Mechanism of Systemic Immunosuppression Li J, Karakas D, Xue F, Chen Y, Zhu G, Yucel YH, MacParland SA, Zhang H, Semple JW, Freedman J, Shi Q, Ni H 2023 Research View Researchers Basic research
Transfusion medicine education delivery in Rwanda: Adapting Transfusion Camp to a resource-limited setting Skelton T, Nizeyimana F, Pendergrast J, Hagumimana J, Masaisa F, Kanyamuhunga A, Gashaija C, Callum J, Pavenski K, Khandelwal A, Lieberman L, Chargé S, Kapitany C, Morgan M, Meirovich H, Lin Y 2023 Transfusion View Health care providers Education research
Modulation of Neutrophil Function by Recombinant Human IgG1 Fc Hexamer in the Endogenous K/BxN Mouse Model of Rheumatoid Arthritis Almizraq RJ, Frias Boligan K, Lewis BJB, Cen S, Whetstone H, Spirig R, Käsermann F, Campbell IK, von Gunten S, Branch DR 2023 Pharmacology View Researchers Basic research