Our Research Publications

Updated August 2025

Title Authors Year Journal Link to Article Intended Audience Purpose
ResearchUnit: Supporting evidence to change regulations regarding the storage of cryosupernatant plasma. Sheffield W 2013 Blood.ca website View Other Other
The impact of prolonged storage of red blood cells on cancer survival Kekre N, Mallick R, Allan D, Tinmouth A, Tay J 2013 PLoS One View Health care providers Clinical research
Co-stimulation with LPS or Poly I:C markedly enhances the anti-platelet immune response and severity of fetal and neonatal alloimmune thrombocytopenia Li C, Chen P, Vadasz B, Ma L, Zhou H, Lang S, Freedman J, Ni H 2013 Thromb Haemost View Researchers Basic research
Quality of red blood cells washed using the ACP 215 cell processor: assessment of optimal pre- and postwash storage times and conditions Hansen A, Yi QL, Acker JP 2013 Transfusion View Researchers New or improved product or process
Adjudication of bleeding outcomes in an international thromboprophylaxis trial in critical illness Arnold DM, Lauzier F, Rabbat C, Zytaruk N, Barlow Cash B, Clarke F, Heels-Ansdell D, Guyatt G, Walter SD, Davies A, Cook DJ, PROTECT Investigators on behalf of the Canadian Critical Care Trials Group and the Australian and New Zealand Intensive Care Clinical Trials Group 2013 Thromb Res View Researchers Clinical research
Challenges in the management of the blood supply Williamson LM, Devine DV 2013 Lancet View Blood operators Other
Fusion of the C-terminal triskaidecapeptide of hirudin variant 3 to alpha1-proteinase inhibitor M358R increases the serpin-mediated rate of thrombin inhibition Roddick LA, Bhakta V, Sheffield W 2013 BMC Biochem View Researchers Basic research
Legal Aspects of the Blood System in Canada Reis NM 2013 Public Health Law and Policy in Canada View Other Other
The epidemiology of human T-cell lymphotropic virus types I and II in Canadian blood donors O'Brien SF, Goldman M, Scalia V, Yi QL, Fan W, Xi G, Dines IR, Fearon MA 2013 Transfus Med View Blood operators Clinical research
Evaluating the role of IL-11, a novel cytokine in the IL-6 family, in a mouse model of spinal cord injury Cho N, Nguyen DH, Satkunendrarajah K, Branch DR, Fehlings MG 2012 J Neuroinflammation View Researchers Basic research
Tissue factor and glycoprotein C on herpes simplex virus type 1 are protease-activated receptor 2 cofactors that enhance infection Sutherland MR, Ruf W, Pryzdial EL 2012 Blood View Researchers Basic research
The importance of haemophilia treatment centre administrators in patient care Almonte T, Decker K, Seroski W, Walker I, Webert K, Bos C, Strike K, Waterhouse L, Goldsmith R, Chan AK 2012 Haemophilia View Health care providers Other
Acquired hemophilia A Webert KE 2012 Semin Thromb Hemost View Health care providers Other
Influence of architecture of high molecular weight linear and branched polyglycerols on their biocompatibility and biodistribution Imran ul-haq M, Lai BF, Chapanian R, Kizhakkedathu JN 2012 Biomaterials View Researchers Basic research
Preserving and using germplasm and dissociated embryonic cells for conserving Caribbean and Pacific coral Hagedorn M, Carter V, Martorana K, Paresa MK, Acker J, Baums IB, Borneman E, Brittsan M, Byers M, Henley M, Laterveer M, Leong JA, McCarthy M, Meyers S, Nelson BD, Petersen D, Tiersch T, Uribe RC, Woods E, Wildt D 2012 PLoS One View Researchers Basic research
Transfusion reactions: a comparative observational study of blood components produced before and after implementation of semiautomated production from whole blood Semple E, Bowes-Schmidt A, Yi QL, Shimla S, Devine DV 2012 Transfusion View Blood operators New or improved product or process
Red Blood Cell Storage Lesions and Related Transfusion Issues: A Canadian Blood Services Research and Development Symposium Pavenski K, Saidenberg E, Lavoie M, Tokessy M, Branch DR 2012 Transfus Med Rev View Health care providers Other
Decreased indoleamine 2,3-dioxygenase expression in dendritic cells and role of indoleamine 2,3-dioxygenase-expressing dendritic cells in immune thrombocytopenia Xu SQ, Wang CY, Zhu XJ, Dong XY, Shi Y, Peng J, Qin P, Sun JZ, Guo C, Ni H, Hou M 2012 Ann Hematol View Researchers Basic research
Thrombin generates previously unidentified C5 products that support the terminal complement activation pathway Krisinger MJ, Goebeler V, Lu Z, Meixner SC, Myles T, Pryzdial EL, Conway EM 2012 Blood View Researchers Basic research
The repertoire and features of human platelet microRNAs Ple H, Landry P, Benham A, Coarfa C, Gunaratne PH, Provost P 2012 PLoS One View Researchers Basic research
Reduction of thrombus size in murine models of thrombosis following administration of recombinant alpha1-proteinase inhibitor mutant proteins Sheffield WP, Eltringham-Smith LJ, Bhakta V, Gataiance S 2012 Thromb Haemost View Researchers Basic research
SHP-1 protein tyrosine phosphatase associates with the adaptor protein CrkL Evren S, Ma XZ, Sakac D, Branch DR 2012 Exp Hematol View Researchers Basic research
Toward a prophylaxis against fetal and neonatal alloimmune thrombocytopenia: induction of antibody-mediated immune suppression and prevention of severe clinical complications in a murine model Tiller H, Killie MK, Chen P, Eksteen M, Husebekk A, Skogen B, Kjeldsen-Kragh J, Ni H 2012 Transfusion View Researchers Basic research
An analysis of the bias in red blood cell hemolysis measurement using several analytical approaches Acker JP, Croteau IM, Yi QL 2012 Clin Chim Acta View Researchers New or improved product or process
Expert approaches to common bleeding and thrombotic problems-part I Hayward CP, Webert KE 2012 Semin Thromb Hemost View Health care providers Other
Influence of polymer architecture on antigens camouflage, CD47 protection and complement mediated lysis of surface grafted red blood cells Chapanian R, Constantinescu I, Rossi NA, Medvedev N, Brooks DE, Scott MD, Kizhakkedathu JN 2012 Biomaterials View Researchers Basic research
The impact of increasing the upper age limit of donation on the eligible blood donor population in Canada Fan W, Yi QL, Xi G, Goldman M, Germain M, O'Brien SF 2012 Transfus Med View Blood operators New or improved product or process
The platelet "sugar high" in diabetes Ni H 2012 Blood View Researchers Other
A prospective study measuring the development of antibodies against platelet factor 4-heparin in healthy males after exposure to heparins Kelton JG, Warkentin TE, Moore JC, Arnold DM, Nazi I, Arepally GM, Roach JM, Fier I 2012 J Thromb Haemost View Health care providers Clinical research
Changes in coagulation factor activity and content of di(2-ethylhexyl)phthalate in frozen plasma units during refrigerated storage for up to five days after thawing Sheffield WP, Bhakta V, Mastronardi C, Ramirez-Arcos S, Howe D, Jenkins C 2012 Transfusion View Health care providers New or improved product or process
Impact of Pandemic Influenza A (H1N1) on Laboratory Services Patel SN, Gubbay JB, Bastien N, Booth T, Charest H, Chernesky M, Couillard M, Drews S, Garceau R, Gubbay J, Guercio S, Fearon M, Fonseca K, Hatchette T, Horsman G, Larke B, Li Y, Majury A, Ouellette O, Petric M, Ratnam S, Sevenhuysen C, Van Caeseele P 2012 National Collaborating Centre for Infectious Diseases: Evidence Reviews on Pandemic H1N1 View Health care providers Other
Selective testing for Trypanosoma cruzi: the first year after implementation at Canadian Blood Services O'Brien SF, Scalia V, Goldman M, Fan W, Yi QL, Dines IR, Huang M, Ndao M, Fearon MA 2012 Transfusion View Blood operators New or improved product or process
Relative efficacy of steroid therapy in immune thrombocytopenia mediated by anti-platelet GPIIbIIIa versus GPIb? antibodies Zeng Q, Zhu L, Tao L, Bao J, Yang M, Simpson EK, Li C, van der Wal DE, Chen P, Spring CM, Wang M, Zhang L, Ruan C, Hou M, Xia R, Ni H 2012 Am J Hematol View Researchers Clinical research
The expanding family of bone marrow homing factors for hematopoietic stem cells: stromal derived factor 1 is not the only player in the game Ratajczak MZ, Kim C, Janowska-Wieczorek A, Ratajczak J 2012 ScientificWorldJournal View Researchers Basic research
The role of complement in the trafficking of hematopoietic stem/progenitor cells Janowska-Wieczorek A, Marquez-Curtis LA, Shirvaikar N, Ratajczak MZ 2012 Transfusion View Researchers Basic research
Low-intensity pulsed ultrasound-mediated stimulation of hematopoietic stem/progenitor cell viability, proliferation and differentiation in vitro Xu P, Gul-Uludag H, Ang WT, Yang X, Huang M, Marquez-Curtis L, McGann L, Janowska-Wieczorek A, Xing J, Swanson E, Chen J 2012 Biotechnol Lett View Researchers Basic research
Platelet antibodies and fetal growth: maternal antibodies against fetal platelet antigen 1a are strongly associated with reduced birthweight in boys Tiller H, Killie MK, Husebekk A, Skogen B, Ni H, Kjeldsen-Kragh J, Olan P 2012 Acta Obstet Gyn Scan View Health care providers Clinical research
Riboflavin and ultraviolet light treatment potentiates vasodilator-stimulated phosphoprotein Ser-239 phosphorylation in platelet concentrates during storage Schubert P, Culibrk B, Coupland D, Scammell K, Gyongyossy-Issa M, Devine DV 2012 Transfusion View Researchers Basic research
Donor motivation in Xi'an, China: comparison with Canadian donors O'Brien SF, Shao ZJ, Osmond L, Yi QL, Li CY, An QX 2012 Vox Sang View Blood operators Other
Herpesviruses enhance fibrin clot lysis Gershom ES, Vanden Hoek AL, Meixner SC, Sutherland MR, Pryzdial EL 2012 Thromb Haemost View Researchers Basic research
Kruppel-like factor 1 (KLF1), KLF2, and Myc control a regulatory network essential for embryonic erythropoiesis Pang CJ, Lemsaddek W, Alhashem YN, Bondzi C, Redmond LC, Ah-Son N, Dumur CI, Archer KJ, Haar JL, Lloyd JA, Trudel M 2012 Mol Cell Biol View Researchers Basic research
Measures to prevent transfusion-related acute lung injury (TRALI) Reesink HW, Lee J, Keller A, Dennington P, Pink J, Holdsworth R, Schennach H, Goldman M, Petraszko T, Sun J, Meng Y, Qian K, Rehacek V, Turek P, Krusius T, Juvonen E, Tiberghien P, Legrand D, Semana G, Muller JY, Bux J, Reil A, Lin CK, Daly H, McSweeney E, Porretti L, Greppi N, Rebulla P, Okazaki H, Sanchez-Guerrero SA, Baptista-Gonzalez HA, Martinez-Murillo C, Guerra-Marquez A, Rodriguez-Moyado H, Middelburg RA, Wiersum-Osselton JC, Brand A, van Tilburg C, Dinesh D, Dagger J, Dunn P, Brojer E, Letowska M, Maslanka K, Lachert E, Uhrynowska M, Zhiburt E, Palfi M, Berlin G, Frey BM, Puig Rovira L, Muniz-Diaz E, Castro E, Chapman C, Green A, Massey E, Win N, Williamson L, Silliman CC, Chaffin DJ, Ambruso DR, Blumberg N, Tomasulo P, Land KJ, Norris PJ, Illoh OC, Davey RJ, Benjamin RJ, Eder AF, McLaughlin L, Kleinman S, Panzer S 2012 Vox Sang View Blood operators Benchmarking and standard setting
Serratia marcescens strains implicated in adverse transfusion reactions form biofilms in platelet concentrates and demonstrate reduced detection by automated culture Greco-Stewart VS, Brown EE, Parr C, Kalab M, Jacobs MR, Yomtovian RA, Ramirez-Arcos SM 2012 Vox Sang View Blood operators Basic research
Lessons learned from Trypanosoma cruzi test implementation Menitove JE, Leach-Bennett J, Sher G 2012 Transfusion View Blood operators Other
Mouse background and IVIG dosage are critical in establishing the role of inhibitory Fcgamma receptor for the amelioration of experimental ITP Leontyev D, Katsman Y, Branch DR 2012 Blood View Researchers Basic research
Optimization of platelet concentrate quality: Application of proteomic technologies to donor management Schubert P, Culibrk B, Karwal S, Slichter SJ, Devine DV 2012 J Proteomics View Blood operators Basic research
Platelets in Thrombosis and Hemostasis: Old Topic with New Mechanisms Wang Y, Andrews M, Yang Y, Lang S, Jin JW, Cameron-Vendrig A, Zhu G, Reheman A, Ni H 2012 Cardiovasc Hematol Disord Drug Targets View Health care providers Basic research
Quality of Red Blood Cells Isolated from Umbilical Cord Blood Stored at Room Temperature Zhurova M, Akabutu J, Acker J 2012 J Blood Transfus View Researchers New or improved product or process
A flow cytometric method for platelet counting in platelet concentrates van der Meer PF, Karssing-van Leeuwen W, Kurtz J, Spengler H-P, Blair A, Devine D, Harrison P, Lambrecht B, VandenBroeke T, de Wildt J, de Korte D, on behalf of the Biomedical Excellence for Safer Transfusion C 2012 Transfusion View Researchers New or improved product or process
Hematopoietic Stem Cell Mobilization and Homing after Transplantation: The Role of MMP-2, MMP-9, and MT1-MMP Shirvaikar N, Marquez-Curtis LA, Janowska-Wieczorek A 2012 Biochem Res Int View Researchers Basic research