Our Research Publications

Updated August 2025

Title Authors Year Journal Link to Article Intended Audience Purpose
Strain-promoted azide-alkyne cycloaddition for protein-protein coupling in the formation of a bis-hemoglobin as a copper-free oxygen carrier Singh S, Dubinsky-Davidchik IS, Kluger R 2016 Org Biomol Chem View Researchers Basic research
Quality and Safety of Blood Products Ramirez-Arcos S, Marks DC, Acker JP, Sheffield WP 2016 J Blood Transfus View Researchers Other
ResearchUnit: Older blood as good as new: no harmful effects of storage time before transfusion Heddle N 2016 Blood.ca website View Other Other
Stability of coagulation protein activities in single units or pools of cryoprecipitate during storage at 20–24°C for up to 24 h Sheffield WP, Bhakta V, Jenkins C 2016 Vox Sang View Blood operators New or improved product or process
Targeting FcRs to treat antibody-dependent autoimmunity Yu X, Lazarus AH 2016 Autoimmun Rev View Researchers Other
Alleviation of gram-negative bacterial lung inflammation by targeting HECTD2 Kapur R, Semple JW 2016 Ann Transl Med View Researchers Basic research
Dengue virus persists and replicates during storage of platelet and red blood cell units Sutherland MR, Simon AY, Serrano K, Schubert P, Acker JP, Pryzdial ELG 2016 Transfusion View Researchers Basic research
Effects of methoxypoly (Ethylene glycol) mediated immunocamouflage on leukocyte surface marker detection, cell conjugation, activation and alloproliferation Kyluik-Price DL, Scott MD 2016 Biomaterials View Researchers Basic research
Evaluating the "family veto" of consent for organ donation Toews M, Caulfield T 2016 CMAJ View Health care providers Other
Introducing the red cell storage lesion Chen D, Serrano K, Devine DV 2016 ISBT Sci Ser View Blood operators Basic research
Myasthenia gravis treated with autologous hematopoietic stem cell transplantation Bryant A, Atkins H, Pringle C, Allan D, Anstee G, Bence-Bruckler I, Hamelin L, Hodgins M, Hopkins HS, Huebsch L, McDiarmid S, Sabloff M, Sheppard D, Tay J, Bredeson C 2016 JAMA Neurol View Researchers Clinical research
Plasma and cryoprecipitate for transfusion Stanworth SJ, Tinmouth AT 2016 Rossi's Principles of Transfusion Medicine View Researchers Basic research
Thymic-derived tolerizing dendritic cells are upregulated in the spleen upon treatment with intravenous immunoglobulin in a murine model of immune thrombocytopenia Kapur R, Aslam R, Kim M, Guo L, Ni H, Segel GB, Semple JW 2016 Platelets View Researchers Basic research
Raman spectroscopy as a novel tool for monitoring biochemical changes and inter-donor variability in stored red blood cell units Atkins CG, Buckley K, Chen D, Schulze HG, Devine DV, Blades MW, Turner RFB 2016 Analyst View Researchers New or improved product or process
The nonhemostatic immune functions of platelets Kapur R, Semple JW 2016 Semin Hematol View Researchers Basic research
Thrombocytopenic syndromes in pregnancy Yan M, Malinowski AK, Shehata N 2016 Obstet Med View Health care providers Clinical research
Corticosteroids compared with intravenous immunoglobulin for the treatment of immune thrombocytopenia in pregnancy Sun D, Shehata N, Ye XY, Gregorovich S, De France B, Arnold DM, Shah PS, Malinowski AK 2016 Blood View Researchers Clinical research
ResearchUnit: Hijacked: the role of platelets in dengue virus infection revealed Pryzdial EL 2016 Blood.ca website View Other Other
Resolving variable maternal D typing using serology and genotyping in selected prenatal patients Clarke G, Hannon J, Berardi P, Barr G, Cote J, Fallis R, Alport T, Lane D, Petraszko T, Ochoa G, Goldman M 2016 Transfusion View Health care providers New or improved product or process
Self-Assembly of a Functional Triple Protein: Hemoglobin-Avidin-Hemoglobin via Biotin–Avidin Interactions Singh S, Kluger R 2016 Biochemistry View Researchers Basic research
The entity of immunoglobulin A-related anaphylactic transfusion reactions is not evidence based Sandler SG, Eder AF, Goldman M, Winters JL 2015 Transfusion View Health care providers Clinical research
A phase-II sequential case-series study of all patients presenting to four plasma exchange centres with presumed relapsed/refractory thrombotic thrombocytopenic purpura treated with rituximab Clark WF, Rock G, Barth D, Arnold DM, Webert KE, Yenson PR, Kelton JG, Li L, Foley SR, members of the Canadian Apheresis G 2015 Br J Haematol View Health care providers Clinical research
Dicer cleavage by calpain determines platelet microRNA levels and function in diabetes Elgheznawy A, Shi L, Hu J, Wittig I, Laban H, Pircher J, Mann A, Provost P, Randriamboavonjy V, Fleming I 2015 Circ Res View Researchers Basic research
Effect of a thrombopoietin receptor agonist on use of intravenous immune globulin in patients with immune thrombocytopenia Zeller MP, Heddle NM, Kelton JG, Hamilton K, Wang G, Sholapur N, Carruthers J, Hsia C, Blais N, Toltl L, Hamm C, Pearson M-A, Arnold DM 2015 Transfusion View Health care providers Clinical research
Further evidence that paroxysmal nocturnal haemoglobinuria is a disorder of defective cell membrane lipid rafts Ratajczak MZ, Borkowska S, Mierzejewska K, Kucia M, Mendek-Czajkowska E, Suszynska M, Sharma VA, Deptala A, Song W, Platzbecker U, Larratt L, Janowska-Wieczorek A, Maciejewski J, Ratajczak J 2015 J Cell Mol Med View Researchers Basic research
Regenerative Therapy and Immune Modulation Using Umbilical Cord Blood-Derived Cells Damien P, Allan DS 2015 Biol Blood Marrow Transplant View Health care providers Other
Effects of pathogen reduction systems on platelet microRNAs, mRNAs, activation, and function Osman A, Hitzler WE, Meyer CU, Landry P, Corduan A, Laffont B, Boilard E, Hellstern P, Vamvakas EC, Provost P 2015 Platelets View Researchers Basic research
Improved Prediction of CD34+ Cell Yield before Peripheral Blood Hematopoietic Progenitor Cell Collection Using a Modified Target Value–Tailored Approach Sheppard D, Tay J, Palmer D, Xenocostas A, Doulaverakis C, Huebsch L, McDiarmid S, Tinmouth A, Mallick R, Martin L, Birch P, Hamelin L, Allan D, Bredeson C 2015 Biol Blood Marrow Transplant View Health care providers New or improved product or process
Plasma and Plasma Protein Product Transfusion: A Canadian Blood Services Centre for Innovation Symposium Zeller MP, Al-Habsi KS, Golder M, Walsh GM, Sheffield WP 2015 Transfus Med Rev View Health care providers Other
Reduced deformability of parasitized red blood cells as a biomarker for anti-malarial drug efficacy Deng X, Duffy SP, Myrand-Lapierre M-E, Matthews K, Santoso AT, Du Y-L, Ryan KS, Ma H 2015 Malar J View Researchers New or improved product or process
Raman spectroscopy of stored red blood cells: evaluating clinically-relevant biochemical markers in donated blood Atkins CG, Buckley K, Chen D, Schulze HG, Devine DV, Blades MW, Turner RFB 2015 Clin Biomed Spectrosc Imag IV View Researchers New or improved product or process
ResearchUnit: ABO...K? Investigating if young females need more than ABO-compatible blood Goldman M 2015 Blood.ca website View Other Other
Treatment decision-making among Canadian youth with severe haemophilia: a qualitative approach Lane SJ, Walker I, Chan AK, Heddle NM, Poon MC, Minuk L, Jardine L, Arnold E, Sholapur N, Webert KE 2015 Haemophilia View Health care providers Clinical research
BK virus prophylaxis with levofloxacin--reply Gill JS, Knoll GA, Humar A 2015 JAMA View Other Other
Clinical effects of blood donor characteristics in transfusion recipients: protocol of a framework to study the blood donor-recipient continuum Chasse M, McIntyre L, Tinmouth A, Acker J, English SW, Knoll G, Forster A, Shehata N, Wilson K, van Walraven C, Ducharme R, Fergusson DA 2015 BMJ Open View Researchers Other
Determining the Volume of Additive Solution and Residual Plasma in Whole Blood Filtered and Buffy Coat Processed Red Cell Concentrates Jordan A, Acker J 2015 Transfus Med Hemother View Researchers New or improved product or process
Maternal anti-platelet beta-3 integrins impair angiogenesis and cause intracranial hemorrhage Yougbaré I, Lang S, Yang H, Chen P, Zhao X, Tai W-S, Zdravic D, Vadasz B, Li C, Piran S, Marshall A, Zhu G, Tiller H, Killie MK, Boyd S, Leong-Poi H, Wen X-Y, Skogen B, Adamson SL, Freedman J, Ni H 2015 J Clin Invest View Researchers Basic research
Prophylactic transfusion for pregnant women with sickle cell disease: a systematic review and meta-analysis Malinowski AK, Shehata N, D'Souza R, Kuo KHM, Ward R, Shah PS, Murphy K 2015 Blood View Health care providers Clinical research
Small Molecule Ice Recrystallization Inhibitors Enable Freezing of Human Red Blood Cells with Reduced Glycerol Concentrations Capicciotti CJ, Kurach JDR, Turner TR, Mancini RS, Acker JP, Ben RN 2015 Sci Rep View Researchers New or improved product or process
Intermittent bacteremia detected in an asymptomatic apheresis platelet donor with repeat positive culture for Escherichia coli: a case report Ramirez-Arcos S, Alport T, Goldman M 2015 Transfusion View Blood operators Clinical research
Platelets and platelet alloantigens: lessons from human patients and animal models of fetal and neonatal alloimmune thrombocytopenia Vadasz B, Chen P, Yougbare I, Zdravic D, Li J, Li C, Carrim N, Ni H 2015 Genes Dis View Researchers Other
Virtual screen for repurposing approved and experimental drugs for candidate inhibitors of EBOLA virus infection Veljkovic V, Loiseau PM, Figadere B, Glisic S, Veljkovic N, Perovic VR, Cavanaugh DP, Branch DR 2015 F1000Res View Researchers Basic research
Rights and interests in human bodies and biological materials Toews M, Caulfield T, Nelson E, Ogbogu U, Hartell D 2015 Canadian National Transplant Research Program Fast Policy Facts: Human Bodies and Biological Materials View Other Other
The use of serial outpatient complete blood count (CBC) results to derive biologic variation: a new tool to gauge the acceptability of hematology testing Cembrowski G, Topping K, Versluys K, Tran D, Malick M, Holmes D, Clarke G 2015 Int J Lab Hematol View Health care providers New or improved product or process
A systematic review of definitions and reporting of bleeding outcome measures in haemophilia Chai-Adisaksopha C, Hillis C, Thabane L, Iorio A 2015 Haemophilia View Health care providers Clinical research
Alloimmune Red Blood Cell Antibodies: Prevalence and Pathogenicity in a Canadian Prenatal Population Zwingerman R, Jain V, Hannon J, Zwingerman N, Clarke G 2015 J Obstet Gynaecol Can View Health care providers Clinical research
Desialylation is a mechanism of Fc-independent platelet clearance and a therapeutic target in immune thrombocytopenia Li J, van der Wal DE, Zhu G, Xu M, Yougbare I, Ma L, Vadasz B, Carrim N, Grozovsky R, Ruan M, Zhu L, Zeng Q, Tao L, Zhai Z-m, Peng J, Hou M, Leytin V, Freedman J, Hoffmeister KM, Ni H 2015 Nat Commun View Researchers Basic research
Haematological problems in obstetrics Rodger M, Sheppard D, Gandara E, Tinmouth A 2015 Best Pract Res Clin Obstet Gynaecol View Health care providers Other
Public Perceptions of Pathogen Reduction Technology in the Canadian Donor Blood Supply Gray N, Newbold KB, Lane SJ, Heddle NM, Webert K, Eyles J 2015 ISBT Sci Ser View Blood operators Other
The efficacy and safety of heparin in patients with sepsis: a systematic review and metaanalysis Zarychanski R, Abou-Setta AM, Kanji S, Turgeon AF, Kumar A, Houston DS, Rimmer E, Houston BL, McIntyre L, Fox-Robichaud AE, Hebert P, Cook DJ, Fergusson DA 2015 Crit Care Med View Health care providers Clinical research