Our Research Publications

Updated August 2025

Title Authors Year Journal Link to Article Intended Audience Purpose
An evaluation of overall effectiveness and treatment satisfaction with intravenous immunoglobulin among patients with immune thrombocytopenia Sholapur NS, Hamilton K, Butler L, Heddle NM, Arnold DM 2016 Transfusion View Researchers Clinical research
High-dose dexamethasone compared with prednisone for previously untreated primary immune thrombocytopenia: a systematic review and meta-analysis Mithoowani S, Gregory-Miller K, Goy J, Miller MC, Wang G, Noroozi N, Kelton JG, Arnold DM 2016 Lancet Haematol View Researchers Clinical research
Molecular immunohaematology round table discussions at the AABB Annual Meeting, Anaheim 2015 Flegel WA, Castilho L, Heaton WA, Keller MA, Klapper EB, Lane WJ, Pirenne F, Shehata N, Stack G, St-Louis M, Tormey CA, Wagner FF, Waxman DA, Denomme GA 2016 Transfusion View Health care providers Clinical research
Platelet transfusion therapy in sub-Saharan Africa: bacterial contamination, recipient characteristics, and acute transfusion reactions Hume HA, Ddungu H, Angom R, Baluku H, Kajumbula H, Kyeyune-Byabazaire D, Orem J, Ramirez-Arcos S, Tobian AA 2016 Transfusion View Researchers Basic research
ResearchUnit: United we stand, divided we fall: using monoclonal antibody combinations to improve drug effectiveness Lazarus A 2016 Blood.ca website View Other Other
Stability of Thawed Apheresis Fresh-Frozen Plasma Stored for up to 120 Hours at 1° C to 6° C Sheffield WP, Bhakta V, Yi Q-L, Jenkins C 2016 J Blood Transfus View Researchers Basic research
Temperature stability of Poly-[hemoglobin-superoxide dismutase-catalase-carbonic anhydrase] in the form of a solution or in the lyophilized form during storage at -80°C, 4°C, 25°C and 37°C or pasteurization at 70°C Bian Y, Guo C, Chang T 2016 Artif Cells Nanomed Biotechnol View Researchers Basic research
Transfusion thresholds and other strategies for guiding allogeneic red blood cell transfusion Carson JL, Stanworth SJ, Roubinian N, Fergusson DA, Triulzi D, Doree C, Hebert PC 2016 Cochrane Database Syst Rev View Health care providers Clinical research
Validation of administrative database codes for acute kidney injury in kidney transplant recipients Molnar AO, van Walraven C, McArthur E, Fergusson D, Garg AX, Knoll G 2016 Can J Kidney Health Dis View Regulators New or improved product or process
Thymic-derived tolerizing dendritic cells are upregulated in the spleen upon treatment with intravenous immunoglobulin in a murine model of immune thrombocytopenia Kapur R, Aslam R, Kim M, Guo L, Ni H, Segel GB, Semple JW 2016 Platelets View Researchers Basic research
A Rapid Screening Assay Identifies Monotherapy with Interferon-ß and Combination Therapies with Nucleoside Analogs as Effective Inhibitors of Ebola Virus McCarthy SDS, Majchrzak-Kita B, Racine T, Kozlowski HN, Baker DP, Hoenen T, Kobinger GP, Fish EN, Branch DR 2016 PLoS Negl Trop Dis View Researchers Basic research
Deformability based sorting of red blood cells improves diagnostic sensitivity for malaria caused by Plasmodium falciparum Guo Q, Duffy SP, Matthews K, Deng X, Santoso AT, Islamzada E, Ma H 2016 Lab Chip View Researchers New or improved product or process
Platelets, immune-mediated thrombocytopenias, and fetal hemorrhage Xu XR, Gallant RC, Ni H 2016 Thromb Res View Researchers Basic research
Protein translation occurs in platelet concentrates despite riboflavin/UV light pathogen inactivation treatment Schubert P, Culibrk B, Karwal S, Goodrich RP, Devine DV 2016 Proteomics Clin Appl View Researchers Basic research
Triplets with neonatal alloimmune thrombocytopenia due to antibodies against human platelet antigen 1a Solh Z, Breakey V, Murthy P, Smith JW, Arnold DM 2016 Transfusion View Health care providers Clinical research
Alteration of blood clotting and lung damage by protamine are avoided using the heparin and polyphosphate inhibitor UHRA Kalathottukaren MT, Abraham L, Kapopara PR, Lai BFL, Shenoi RA, Rosell FI, Conway EM, Pryzdial ELG, Morrissey JH, Haynes CA, Kizhakkedathu JN 2016 Blood View Researchers Basic research
Detection of bacterial adherence and biofilm formation on medical surfaces Loza-Correa M, Ramirez-Arcos S 2016 Biofilms and implantable medical devices: infection and control View Researchers New or improved product or process
Elevation of C-reactive protein levels in patients with transfusion-related acute lung injury Kapur R, Kim M, Rondina MT, Porcelijn L, Semple JW 2016 Oncotarget View Researchers Basic research
Small molecule ice recrystallization inhibitors mitigate red blood cell lysis during freezing, transient warming and thawing Briard JG, Poisson JS, Turner TR, Capicciotti CJ, Acker JP, Ben RN 2016 Sci Rep View Researchers New or improved product or process
Transfusion-related alloimmunization in children: epidemiology and effects of chemotherapy Solh Z, Athale U, Arnold DM, Cook RJ, Foley R, Heddle NM 2016 Vox Sang View Health care providers Clinical research
Acute Lung Injury Causes Asynchronous Alveolar Ventilation That Can Be Corrected by Individual Sighs Tabuchi A, Nickles HT, Kim M, Semple JW, Koch E, Brochard L, Slutsky AS, Pries AR, Kuebler WM 2015 Am J Respir Crit Care Med View Health care providers Clinical research
Inhibition of phagocytic recognition of anti-D opsonized Rh D+ RBC by polymer-mediated immunocamouflage Li L, Noumsi GT, Kwok YYE, Moulds JM, Scott MD 2015 Am J Hematol View Researchers Basic research
Molecular immunohaematology round table discussions at the AABB Annual Meeting, Philadelphia 2014 Flegel WA, De Castilho SL, Keller MA, Klapper EB, Moulds JM, Noizat-Pirenne F, Shehata N, Stack G, St-Louis M, Tormey CA, Waxman DA, Weinstock C, Wendel S, Denomme GA 2015 Blood Transfus View Health care providers Other
Perioperative Management of Dabigatran: A Prospective Cohort Study Schulman S, Carrier M, Lee AY, Shivakumar S, Blostein M, Spencer FA, Solymoss S, Barty R, Wang G, Heddle N, Douketis JD 2015 Circulation View Health care providers Clinical research
ResearchUnit: Bath time for blood cells: improving the red blood cell washing process Acker JP 2015 Blood.ca website View Other Other
ResearchUnit: Using Immunocamouflage to Fool the Immune System Scott MD 2015 Blood.ca website View Other Other
Validation of sterility testing of cord blood: Challenges and results Ramirez-Arcos S, Kou Y, Yang L, Perkins H, Taha M, Halpenny M, Elmoazzen H 2015 Transfusion View Blood operators New or improved product or process
Reduced deformability of parasitized red blood cells as a biomarker for anti-malarial drug efficacy Deng X, Duffy SP, Myrand-Lapierre M-E, Matthews K, Santoso AT, Du Y-L, Ryan KS, Ma H 2015 Malar J View Researchers New or improved product or process
A benchmarking program to reduce red blood cell outdating: implementation, evaluation, and a conceptual framework Barty RL, Gagliardi K, Owens W, Lauzon D, Scheuermann S, Liu Y, Wang G, Pai M, Heddle NM 2015 Transfusion View Health care providers Benchmarking and standard setting
Aggregates in platelet concentrates van der Meer PF, Dumont LJ, Lozano M, Bondar N, Wong J, Ismay S, Pink J, Nussbaumer W, Coene J, Feys HB, Compernolle V, Devine DV, Howe D, Lin CK, Sun J, Ringwald J, Strasser EF, Eckstein R, Seltsam A, Perseghin P, Proserpio P, Wakamoto S, Akino M, Takamoto S, Tadokoro K, Teo D, Shu PH, Chua SS, Jimenez-Marco T, Lozano M, Cid J, Castro E, Munoz I, Gulliksson H, Sandgren P, Thomas S, Petrik J, McColl K, Kamel H, Dugger J, Sweeney JD, Gorlin JB, Sutor LJ, Heath D, Sayers MH 2015 Vox Sang View Blood operators Benchmarking and standard setting
Anti-A and anti-B: what are they and where do they come from? Branch DR 2015 Transfusion View Researchers Other
Chapter 33: Synthesis of N-(4-Methoxybenzyl)-2-(α-d-glucopyranosyl) acetamide Roy R, Vidal S, Briard JG, Shiao TC, Ben RN 2015 Carbohydrate Chemistry: Proven Synthetic Methods, Volume 3 View Researchers Basic research
Dissociation of SERPINE1 mRNA from the translational repressor proteins Ago2 and TIA-1 upon platelet activation Corduan A, Ple H, Laffont B, Wallon T, Plante I, Landry P, Provost P 2015 Thromb Haemost View Researchers Basic research
Intravenous Immunoglobulin (IVIg) Utilization in Immune Thrombocytopenia (ITP): A Multi-Center, Retrospective Review Hsia C, Liu Y, Eckert K, Monga N, Elia-Pacitti J, Heddle NM 2015 Drugs Real World Outcomes View Health care providers Clinical research
Red blood cell transfusion and mortality effect in aneurysmal subarachnoid hemorrhage: a systematic review and meta-analysis protocol English SW, Chassé M, Turgeon AF, Tinmouth A, Boutin A, Pagliarello G, Fergusson D, McIntyre L 2015 Syst Rev View Researchers Clinical research
Evaluation of the appropriateness of frozen plasma usage after introduction of prothrombin complex concentrates: a retrospective study Shih AW, Kolesar E, Ning S, Manning N, Arnold DM, Crowther MA 2015 Vox Sang View Health care providers New or improved product or process
Hemoglobin C in a patient with sickle cell anemia: Transfusion-acquired SC disease Estey MP, Capote KR, Barakauskas VE, Clarke G, Higgins T 2015 Clin Biochem View Health care providers Clinical research
New cancers after autotransplantations for multiple myeloma Mahindra A, Raval G, Mehta P, Brazauskas R, Zhang MJ, Zhong X, Bird JM, Freytes CO, Hale GA, Herzig R, Holmberg LA, Kamble RT, Kumar S, Lazarus HM, Majhail NS, Marks DI, Moreb JS, Olsson R, Saber W, Savani BN, Schiller GJ, Tay J, Vogl DT, Waller EK, Wiernik PH, Wirk B, Lonial S, Krishnan AY, Dispenzieri A, Brandenburg NA, Gale RP, Hari PN 2015 Biol Blood Marrow Transplant View Health care providers Clinical research
Risk infection to spare bleeding? The quandary of splenectomy for immune thrombocytopenia Zeller M, Arnold DM 2015 Am J Hematol View Health care providers Clinical research
Virtual screen for repurposing approved and experimental drugs for candidate inhibitors of EBOLA virus infection Veljkovic V, Loiseau PM, Figadere B, Glisic S, Veljkovic N, Perovic VR, Cavanaugh DP, Branch DR 2015 F1000Res View Researchers Basic research
A novel nanobiotherapeutic poly-[hemoglobin-superoxide dismutase-catalase-carbonic anhydrase] with no cardiac toxicity for the resuscitation of a rat model with 90 minutes of sustained severe hemorrhagic shock with loss of 2/3 blood volume Bian Y, Chang TM 2015 Artif Cells Nanomed Biotechnol View Researchers Basic research
CD8+ T cells are predominantly protective and required for effective steroid therapy in murine models of immune thrombocytopenia Ma L, Simpson E, Li J, Xuan M, Xu M, Baker L, Shi Y, Yougbaré I, Wang X, Zhu G, Chen P, Prudhomme GJ, Lazarus AH, Freedman J, Ni H 2015 Blood View Researchers Basic research
Platelet transfusion: a systematic review of the clinical evidence Kumar A, Mhaskar R, Grossman BJ, Kaufman RM, Tobian AA, Kleinman S, Gernsheimer T, Tinmouth AT, Djulbegovic B 2015 Transfusion View Health care providers Clinical research
ResearchUnit: Breakthrough brings universal blood a step closer to reality Withers SG, Kizhakkedathu J 2015 Blood.ca website View Other Other
Storage duration and other measures of quality of red blood cells for transfusion Spinella PC, Acker J 2015 JAMA View Blood operators Other
Public Perceptions of Pathogen Reduction Technology in the Canadian Donor Blood Supply Gray N, Newbold KB, Lane SJ, Heddle NM, Webert K, Eyles J 2015 ISBT Sci Ser View Blood operators Other
The efficacy and safety of heparin in patients with sepsis: a systematic review and metaanalysis Zarychanski R, Abou-Setta AM, Kanji S, Turgeon AF, Kumar A, Houston DS, Rimmer E, Houston BL, McIntyre L, Fox-Robichaud AE, Hebert P, Cook DJ, Fergusson DA 2015 Crit Care Med View Health care providers Clinical research
The prevalence of anti-K in Canadian prenatal patients Goldman M, Lane D, Webert K, Fallis R 2015 Transfusion View Health care providers Clinical research
Western immunoblotting as a new tool for investigating direct antiglobulin test-negative autoimmune hemolytic anemias Bloch EM, Sakac D, Branch HA, Cserti-Gazdewich C, Pendergrast J, Pavenski K, Branch DR 2015 Transfusion View Health care providers New or improved product or process
A biochemical network can control formation of a synthetic material by sensing numerous specific stimuli Hun Yeon J, Chan KYT, Wong T-C, Chan K, Sutherland MR, Ismagilov RF, Pryzdial ELG, Kastrup CJ 2015 Sci Rep View Researchers Basic research