Our Research Publications

Updated August 2025

Title Authors Year Journal Link to Article Intended Audience Purpose
Platelet Transfusion Practices in the Intensive Care Unit: Data from a Large Transfusion Registry Ning S, Barty R, Liu Y, Heddle NM, Rochwerg B, Arnold DM 2016 Chest View Health care providers Clinical research
Raman spectroscopy as a novel tool for monitoring biochemical changes and inter-donor variability in stored red blood cell units Atkins CG, Buckley K, Chen D, Schulze HG, Devine DV, Blades MW, Turner RFB 2016 Analyst View Researchers New or improved product or process
Stability of coagulation protein activities in single units or pools of cryoprecipitate during storage at 20–24°C for up to 24 h Sheffield WP, Bhakta V, Jenkins C 2016 Vox Sang View Blood operators New or improved product or process
Targeting FcRs to treat antibody-dependent autoimmunity Yu X, Lazarus AH 2016 Autoimmun Rev View Researchers Other
Small-molecule ice recrystallization inhibitors improve the post-thaw function of hematopoietic stem and progenitor cells Briard JG, Jahan S, Chandran P, Allan D, Pineault N, Ben RN 2016 ACS Omega View Researchers Basic research
Defining Significant Events for Neonatal and Pediatric Transport: Results of a Combined Delphi and Consensus Meeting Process Gunz A, McNally J, Whyte H, O'Hearn K, Foster J, Parker M, Dhanani S 2016 J Pediatr Intensive Care View Researchers Clinical research
Extracellular vesicles in transfusion-related immunomodulation and the role of blood component manufacturing Almizraq RJ, Seghatchian J, Acker JP 2016 Transfusion and Apheresis Science View Researchers Basic research
Interpretation of pretransfusion testing in obstetrical patients who have received antepartum Rh immunoglobulin prophylaxis Szkotak AJ, Lunty B, Nahirniak S, Clarke G 2016 Vox Sang View Health care providers Clinical research
Physical characterization of hematopoietic stem cells using multidirectional label-free light scatterings Shahin H, Gupta M, Janowska-Wieczorek A, Rozmus W, Tsui YY 2016 Optics Express View Researchers Basic research
ResearchUnit: Hijacked: the role of platelets in dengue virus infection revealed Pryzdial EL 2016 Blood.ca website View Other Other
Resolving variable maternal D typing using serology and genotyping in selected prenatal patients Clarke G, Hannon J, Berardi P, Barr G, Cote J, Fallis R, Alport T, Lane D, Petraszko T, Ochoa G, Goldman M 2016 Transfusion View Health care providers New or improved product or process
Self-Assembly of a Functional Triple Protein: Hemoglobin-Avidin-Hemoglobin via Biotin–Avidin Interactions Singh S, Kluger R 2016 Biochemistry View Researchers Basic research
The nonhemostatic immune functions of platelets Kapur R, Semple JW 2016 Semin Hematol View Researchers Basic research
Thrombocytopenic syndromes in pregnancy Yan M, Malinowski AK, Shehata N 2016 Obstet Med View Health care providers Clinical research
Rationale and Design of the Informing Fresh versus Old Red Cell Management (INFORM) Trial: An International Pragmatic Randomized Trial Eikelboom JW, Cook RJ, Barty R, Liu Y, Arnold DM, Crowther MA, Devereaux PJ, Ellis M, Figueroa P, Gallus A, Hirsh J, Kurz A, Roxby D, Sessler DI, Sharon Y, Sobieraj-Teague M, Warkentin TE, Webert KE, Heddle NM 2016 Transfus Med Rev View Researchers Clinical research
ResearchUnit: Data mining 2: digging for deeper understanding of donors and transfusion outcome Fergusson DA, Acker J 2016 Blood.ca website View Other Other
The M358R variant of α1-proteinase inhibitor inhibits coagulation factor VIIa Sheffield WP, Bhakta V 2016 Biochem Biophys Res Commun View Researchers Basic research
A trial to determine whether septic shock-reversal is quicker in pediatric patients randomized to an early goal-directed fluid-sparing strategy versus usual care (SQUEEZE): study protocol for a pilot randomized controlled trial Parker MJ, Thabane L, Fox-Robichaud A, Liaw P, Choong K 2016 Trials View Researchers Clinical research
Platelet concentrate functionality assessed by thromboelastography or rotational thromboelastometry Arbaeen AF, Serrano K, Levin E, Devine DV 2016 Transfusion View Researchers Basic research
Quality assessment of established and emerging blood components for transfusion Acker J, Marks DC, Sheffield W 2016 J Blood Transfus View Blood operators Benchmarking and standard setting
Severe bleeding events in adults and children with primary immune thrombocytopenia: a systematic review Neunert C, Noroozi N, Norman G, Buchanan GR, Goy J, Nazi I, Kelton JG, Arnold DM 2015 J Thromb Haemost View Health care providers Clinical research
Surveillance Report 2014 O'Brien SF 2015 Blood.ca website View Other Other
The platelet serotonin-release assay Warkentin TE, Arnold DM, Nazi I, Kelton JG 2015 Am J Hematol View Health care providers Clinical research
L'étude ABLE : un essai clinique randomisé sur l'effet de la durée d'entreposage des concentrés érythrocytaires transfusés en réanimation Lacroix J, Hébert PC, Fergusson D, Tinmouth A, Capellier G, Tiberghien P, Bardiaux L 2015 Transfus Clin Biol View Health care providers Clinical research
Prevention of surface-induced thrombogenesis on poly(vinyl chloride) Fedorov K, Jankowski A, Sheikh S, Blaszykowski C, Reheman A, Romaschin A, Ni H, Thompson M 2015 J Mater Chem B Mater Biol Med View Researchers Basic research
Raman spectroscopy of stored red blood cells: evaluating clinically-relevant biochemical markers in donated blood Atkins CG, Buckley K, Chen D, Schulze HG, Devine DV, Blades MW, Turner RFB 2015 Clin Biomed Spectrosc Imag IV View Researchers New or improved product or process
ResearchUnit: ABO...K? Investigating if young females need more than ABO-compatible blood Goldman M 2015 Blood.ca website View Other Other
Quality of red blood cells washed using a second wash sequence on an automated cell processor Hansen AL, Turner TR, Kurach JDR, Acker JP 2015 Transfusion View Health care providers New or improved product or process
The role of inflammation in intravenous immune globulin-mediated hemolysis Pendergrast J, Willie-Ramharack K, Sampson L, Laroche V, Branch DR 2015 Transfusion View Researchers Clinical research
Human Endothelial Colony-Forming Cells Protect against Acute Kidney Injury: Role of Exosomes Burger D, Viñas JL, Akbari S, Dehak H, Knoll W, Gutsol A, Carter A, Touyz RM, Allan DS, Burns KD 2015 Am J Pathol View Researchers Basic research
Prophylactic transfusion for pregnant women with sickle cell disease: a systematic review and meta-analysis Malinowski AK, Shehata N, D'Souza R, Kuo KHM, Ward R, Shah PS, Murphy K 2015 Blood View Health care providers Clinical research
Treatment decision-making among Canadian youth with severe haemophilia: a qualitative approach Lane SJ, Walker I, Chan AK, Heddle NM, Poon MC, Minuk L, Jardine L, Arnold E, Sholapur N, Webert KE 2015 Haemophilia View Health care providers Clinical research
Recommendations for standardization of laboratory testing for drug-induced immune thrombocytopenia: communication from the SSC of the ISTH Arnold DM, Curtis BR, Bakchoul T, for the Subcommittee on Platelet Immunology 2015 J Thromb Haemost View Health care providers Benchmarking and standard setting
Circular of information for the use of human blood components: Hematopoietic Progenitor Cells (HPC), Cord Blood Jenkins C 2015 Blood.ca website View Health care providers Benchmarking and standard setting
Elevated Abundance, Size, and MicroRNA Content of Plasma Extracellular Vesicles in Viremic HIV-1+ Patients: Correlations With Known Markers of Disease Progression Hubert A, Subra C, Jenabian MA, Tremblay Labrecque PF, Tremblay C, Laffont B, Provost P, Routy JP, Gilbert C 2015 J Acquir Immune Defic Syndr View Researchers Basic research
Hemodialysis for the treatment of dabigatran-associated bleeding: a case report and systematic review Chai-Adisaksopha C, Hillis C, Lim W, Boonyawat K, Moffat K, Crowther M 2015 J Thromb Haemost View Health care providers Clinical research
Major arterial events in patients with chronic myeloid leukemia treated with tyrosine kinase inhibitors: a meta-analysis Chai-Adisaksopha C, Lam W, Hillis C 2015 Leuk Lymphoma View Health care providers Clinical research
Rights and interests in human bodies and biological materials Toews M, Caulfield T, Nelson E, Ogbogu U, Hartell D 2015 Canadian National Transplant Research Program Fast Policy Facts: Human Bodies and Biological Materials View Other Other
Small Molecule Ice Recrystallization Inhibitors Enable Freezing of Human Red Blood Cells with Reduced Glycerol Concentrations Capicciotti CJ, Kurach JDR, Turner TR, Mancini RS, Acker JP, Ben RN 2015 Sci Rep View Researchers New or improved product or process
ResearchUnit: Making the cut: protein breakdown in platelets during storage Serrano K 2015 Blood.ca website View Other Other
Surveillance Report 2015 O'Brien SF 2015 Blood.ca website View Other Other
Impact of a 5-year deferral from blood donation for men who have sex with men O'Brien SF, Osmond L, Fan W, Yi Q-L, Goldman M 2015 Transfusion View Blood operators Benchmarking and standard setting
Inhibition of Autoimmune Diabetes in NOD Mice by miRNA Therapy Wang D, Shanina I, Toyofuku WM, Horwitz MS, Scott MD 2015 PLoS One View Researchers Basic research
Rituximab plus standard of care for treatment of primary immune thrombocytopenia: a systematic review and meta-analysis Chugh S, Darvish-Kazem S, Lim W, Crowther MA, Ghanima W, Wang G, Heddle NM, Kelton JG, Arnold DM 2015 Lancet Haematol View Health care providers Clinical research
The use of serial outpatient complete blood count (CBC) results to derive biologic variation: a new tool to gauge the acceptability of hematology testing Cembrowski G, Topping K, Versluys K, Tran D, Malick M, Holmes D, Clarke G 2015 Int J Lab Hematol View Health care providers New or improved product or process
Transfusion Patterns in All Patients Admitted to the Intensive Care Unit and in Those Who Die in Hospital: A Descriptive Analysis Shehata N, Forster AJ, Lawrence N, Ducharme R, Fergusson DA, Chassé M, Rothwell DM, Hébert PC, Tinmouth AT, Wilson K 2015 PLoS One View Health care providers Clinical research
Age of transfused blood in critically ill adults Lacroix J, Hebert PC, Fergusson DA, Tinmouth A, Cook DJ, Marshall JC, Clayton L, McIntyre L, Callum J, Turgeon AF, Blajchman MA, Walsh TS, Stanworth SJ, Campbell H, Capellier G, Tiberghien P, Bardiaux L, van de Watering L, van der Meer NJ, Sabri E, Vo D 2015 N Engl J Med View Health care providers Clinical research
Back to Anatomy: Improving Landmarking Accuracy of Clinical Procedures Using a Novel Approach to Procedural Teaching Zeller M, Cristancho S, Mangel J, Goldszmidt M 2015 South Med J View Health care providers Other
Comparison of mammalian and bacterial expression library screening to detect recombinant alpha-1 proteinase inhibitor variants with enhanced thrombin inhibitory capacity? Gierczak RF, Bhakta V, Xie M, Sheffield WP 2015 J Biotechnol View Researchers Basic research
Factor XIIIa-dependent retention of red blood cells in clots is mediated by fibrin ?-chain crosslinking Byrnes JR, Duval C, Wang Y, Hansen CE, Ahn B, Mooberry MJ, Clark MA, Johnsen JM, Lord ST, Lam W, Meijers JCM, Ni H, Ariens RAS, Wolberg AS 2015 Blood View Researchers Basic research