Our Research Publications

Updated August 2025

Title Authors Year Journal Link to Article Intended Audience Purpose
Implications of variability in cell membrane permeability for design of methods to remove glycerol from frozen-thawed erythrocytes Lahmann JM, Sanchez CC, Benson JD, Acker JP, Higgins AZ 2020 Cryobiology View Researchers Basic research
Stability of 40 cytokines/chemokines in chronically ill patients under different storage conditions Binnington B, Sakac D, Yi Q, Tong TN, Parmar N, Duong TT, Yeung RSM, Pendergrast J, Branch DR 2020 Cytokine View Researchers Basic research
50 years of Vox Sanguinis International Forums Lozano M, Dunbar NM, Devine DV 2020 Vox Sang View Researchers Benchmarking and standard setting
Centre d’innovation Rapport d’étape annuel 2019-2020 Levy I, Pambrun C 2020 Blood.ca website Other Other
Evaluating blood product quality post expiry to mitigate blood shortages during the COVID-19 pandemic in Canada Turner TR, Olafson C, Mykhailova O, Xu A, Acker JP 2020 Transfusion View Researchers New or improved product or process
Perinatal issues in transfusion practice Lieberman L, Clarke G, Svensson A 2020 AABB Technical Manual, 20th Edition Health care providers Benchmarking and standard setting
Revisiting study design and methodology for pathogen reduced platelet transfusions: a round table discussion Heddle NM, Cardoso M, van der Meer PF 2020 Transfusion View Researchers Clinical research
Transient warming affects potency of cryopreserved cord blood units Pasha R, Howell A, Turner TR, Halpenny M, Elmoazzen H, Acker JP, Pineault N 2020 Cytotherapy View Researchers New or improved product or process
Defocused Spatially Offset Raman Spectroscopy in Media of Different Optical Properties for Biomedical Applications Using a Commercial Spatially Offset Raman Spectroscopy Device Vardaki MZ, Devine DV, Serrano K, Simantiris N, Blades MW, Piret JM, Turner RFB 2020 Appl Spectrosc View Researchers New or improved product or process
IgG3 anti-Kell allotypic variation results in differential antigen binding and phagocytosis Cen SY, Holton MB, Binnington B, Denomme GA, Howie HL, Lebedev JN, Zimring JC, Branch DR 2020 Transfusion View Researchers Basic research
Venous limb gangrene and pulseless electrical activity (PEA) cardiac arrest during management of deep-vein thrombosis and progressive limb ischemic necrosis following vascular surgery Avram AT, Blostein MD, Hirsch AM, Warkentin TE 2020 Am J Hematol View Health care providers Clinical research
Canada's MSM Research Program - producing and mobilizing knowledge Chargé S, Haw J 2020 Transfusion Today Researchers MSM research
Emerging use of machine learning and advanced technologies to assess red cell quality Sebastian JA, Kolios MC, Acker JP 2020 Transfus Apher Sci View Researchers New or improved product or process
Immune thrombocytopenia (ITP) in adults: Second-line and subsequent therapies George J, Arnold D 2020 UptoDate View Health care providers Benchmarking and standard setting
Objective assessment of stored blood quality by deep learning Doan M, Sebastian JA, Caicedo JC, Siegert S, Roch A, Turner TR, Mykhailova O, Pinto RN, McQuin C, Goodman A, Parsons MJ, Wolkenhauer O, Hennig H, Singh S, Wilson A, Acker JP, Rees P, Kolios MC, Carpenter AE 2020 PLoS Pathog View Researchers New or improved product or process
Research Unit: Machine learning throws away the buckets to better understand red blood cell quality Acker JP 2020 Blood.ca website View Researchers Basic research
Transfusion septic reactions involving platelet concentrates contaminated with Citrobacter koseri Ramirez-Arcos S 2020 Ann Blood View Researchers Clinical research
Evaluating the quality of red blood cell concentrates irradiated before or after cryopreservation Turner TR, Lautner L, Hill A, Howell A, Skeate R, Acker JP 2020 Transfusion View Researchers Basic research
Antithrombotics from Frog Skin Secretions Ni H 2020 Thromb Haemost View Researchers Basic research
FcRn is a CD32a coreceptor that determines susceptibility to IgG immune complex-driven autoimmunity Hubbard JJ, Pyzik M, Rath T, Kozicky LK, Sand KMK, Gandhi AK, Grevys A, Foss S, Menzies SC, Glickman JN, Fiebiger E, Roopenian DC, Sandlie I, Andersen JT, Sly LM, Baker K, Blumberg RS 2020 J Exp Med View Researchers Basic research
It's in Me to Give: Canadian Gay, Bisexual, and Queer Men's Willingness to Donate Blood If Eligible Despite Feelings of Policy Discrimination Grace D, Gaspar M, Klassen B, Lessard D, Brennan DJ, Lachowsky NJ, Adam BD, Cox J, Lambert G, Anand P, Jollimore J, Moore D, Hart TA 2020 Qual Health Res View Blood operators MSM research
The utility of a monocyte monolayer assay in the assessment of intravenous immunoglobulin–associated hemolysis Tong TN, Blacquiere M, Sakac D, Burke-Murphy E, Yi Q, Callum J, Cserti-Gazdewich C, Parmar N, Shehata N, Pavenski K, Lau W, Lin Y, Lieberman L, Branch DR, Pendergrast J 2020 Transfusion View Researchers New or improved product or process
Engineering the serpin alpha 1-antitrypsin: A diversity of goals and techniques Scott BM, Sheffield WP 2020 Protein Sci View Researchers Basic research
Platelet vesicles are potent inflammatory mediators in red blood cell products and washing reduces the inflammatory phenotype Almizraq R, Kipkeu B, Acker JP 2020 Transfusion View Researchers Basic research
An AI-Driven Predictive Modelling Framework to Analyze and Visualize Blood Product Transactional Data for Reducing Blood Products’ Discards Rad J, Cheng C, Quinn JG, Abidi S, Liwski R, Abidi SSR 2020 Artificial Intelligence in Medicine View Researchers New or improved product or process
Cryoprotectant-dependent control of intracellular ice recrystallization in hepatocytes using small molecule carbohydrate derivatives William N, Acker JP 2020 Cryobiology View Researchers Basic research
Platelet Disorders Crowther M, Zawilska K, M?ynarski W, Arnold D 2020 McMaster Textbook of Internal Medicine Health care providers Benchmarking and standard setting
Updated Understanding of Platelets in Thrombosis and Hemostasis: The Roles of Integrin PSI Domains and their Potential as Therapeutic Targets MacKeigan DT, Ni T, Shen C, Stratton TW, Ma W, Zhu G, Bhoria P, Ni H 2020 Cardiovasc Hematol Disord Drug Targets View Researchers Basic research
ResearchUnit: Reducing bleeding after cardiac surgery: fibrinogen concentrate vs cryoprecipitate Karkouti K 2020 Blood.ca website View Health care providers Clinical research
The use of IVIg in fetal and neonatal alloimmune thrombocytopenia— Principles and mechanisms Wabnitz H, Khan R, Lazarus AH 2020 Transfus Apher Sci View Researchers Clinical research
Blood donation and the global COVID-19 pandemic: areas for social science research Haw J, Holloway K, Masser B, Merz E-M, Thrope R 2020 Vox Sang View Researchers New or improved product or process
Comparison of short-term mortality between mechanically ventilated patients with COVID-19 and influenza in a setting of sustainable healthcare system Lee J, Lee YH, Chang H-H, Choi SH, Seo H, Yoo SS, Lee SY, Cha SI, Park JY, Kim CH 2020 J Infect View Health care providers Clinical research
High-dose IVIG plus cangrelor platelet "anesthesia" during urgent heparin-CPB in a patient with recent SRA-negative HIT-thrombosis with persisting platelet-activating antibodies Koster A, Nazy I, Birschmann IE, Smith JW, Sheppard JI, Warkentin TE 2020 Res Pract Thromb Haemost View Health care providers Clinical research
Mouse Models of Rheumatoid Arthritis for Studies on Immunopathogenesis and Preclinical Testing of Fc Receptor-Targeting Biologics Lewis BJB, Branch DR 2020 Pharmacology View Researchers Basic research
Safety of blood donation by individuals over age 70 and their contribution to the blood supply in five developed countries: a BEST Collaborative group study Goldman M, Germain M, Gregoire Y, Vassallo RR, Kamel H, Bravo M, Irving DO, Di Angelantonio E, Steele WR, O'Brien SF, for the Biomedical Excellence for Safer Transfusion Collaborative (BEST) Investigators 2019 Transfusion View Blood operators New or improved product or process
45 - Alloimmune Thrombocytopenia Kaplan C, Bertrand G, Ni H 2019 Platelets (Fourth Edition) View Researchers New or improved product or process
Translating red cell "omics" into new perspectives in transfusion medicine: mining the gems in the data mountains Spitalnik SL, Devine DV 2019 Transfusion View Researchers Other
Gay and bisexual men’s views on reforming blood donation policy in Canada: a qualitative study Grace D, Gaspar M, Lessard D, Klassen B, Brennan DJ, Adam BD, Jollimore J, Lachowsky NJ, Hart TA 2019 BMC Public Health View Researchers Other
Management of iron deficiency Ning S, Zeller MP 2019 Hematology Am Soc Hematol Educ Program View Health care providers Clinical research
Réduction des agents pathogènes dans les produits de fractionnement Bigham M 2019 Guide de la pratique transfusionnelle View Health care providers Benchmarking and standard setting
Fetale und neonatale Alloimmun-Thrombozytopenie: Informationen für Patienten International Collaboration for Transfusion Medicine Guidelines 2019 ICTMG.org website View Other Other
Malaria blood safety policy in five non-endemic countries: a retrospective comparison through the lens of the ABO risk-based decision-making framework O'Brien S, Ward S, Gallian P, Fbara C, Pillonel J, Kitchen A, Davison K, Seed C, Gilles D, Steele W, Leiby D 2019 Blood Transfus View Blood operators New or improved product or process
Biological mechanisms implicated in adverse outcomes of sex mismatched transfusions Alshalani A, Li W, Juffermans NP, Seghatchian J, Acker JP 2019 Transfus Apher Sci View Researchers Basic research
Direct comparison of two extended-half-life recombinant FVIII products: a randomized, crossover pharmacokinetic study in patients with severe hemophilia A Shah A, Solms A, Wiegmann S, Ahsman M, Berntorp E, Tiede A, Iorio A, Mancuso ME, Zhivkov T, Lissitchkov T 2019 Ann Hematol View Health care providers Clinical research
Improved in vitro quality of stored red blood cells upon oxygen reduction prior to riboflavin/UV light treatment of whole blood Schubert P, Culibrk B, Chen D, Serrano K, Levin E, Chen Z, Zoescher P, Goodrich RP, Yoshida T, Devine DV 2019 Transfusion View Researchers New or improved product or process
Pertussis vaccine effectiveness in a frequency matched population-based case-control Canadian Immunization Research Network study in Ontario, Canada 2009–2015 Crowcroft NS, Schwartz KL, Chen C, Johnson C, Li Y, Marchand-Austin A, Bolotin S, Jamieson FB, Drews SJ, Russell ML, Svenson LW, Simmonds K, Mahmud SM, Kwong JC 2019 Vaccine View Researchers Clinical research
Massive hemorrhage protocol survey: Marked variability and absent in one-third of hospitals in Ontario, Canada Chin V, Cope S, Yeh CH, Thompson T, Nascimento B, Pavenski K, Callum J 2019 Injury View Health care providers Clinical research
The sensitivity and specificity of platelet autoantibody testing in immune thrombocytopenia: a systematic review and meta-analysis of a diagnostic test Vrbensky JR, Moore JE, Arnold DM, Smith JW, Kelton JG, Nazy I 2019 J Thromb Haemost View Researchers Clinical research
Assessing the Vascular Deformability of Erythrocytes and Leukocytes: From Micropipettes to Microfluidics Scott M, Mathews K, Ma H 2019 Current and Future Aspects of Nanomedicine View Researchers Basic research
One step closer': Acceptability of a programme of plasma donation for fractionation from men who have sex with men Caruso J, Germain M, Godin G, Myhal G, Pronovost P, Morin M, Otis J 2019 Vox Sang View Blood operators Other