Our Research Publications

Updated November 2023

Title Authors Year Journal Link to Article Intended Audience Purpose
Chemoenzymatic Synthesis of a Type 2 Blood Group A Tetrasaccharide and Development of High-throughput Assays Enables a Platform for Screening Blood Group Antigen-cleaving Enzymes Kwan DH, Ernst S, Kotzler MP, Withers SG 2015 Glycobiology View Researchers Basic research
Concentré de recherche: Comment se comportent les bactéries lors de la fabrication des plaquettes? Ramirez-Arcos S 2017 Blood.ca website View Researchers Basic research
Efficacy and safety of regenerative cell therapy for pulmonary arterial hypertension in animal models: a preclinical systematic review protocol Suen CM, Zhai A, Lalu MM, Welsh C, Levac BM, Fergusson D, McIntyre L, Stewart DJ 2016 Syst Rev View Researchers Basic research
Fc-independent phagocytosis: Implications for IVIG and other therapies in immune-mediated thrombocytopenia Li J, van der Wal DE, Zhu L, Vadasz B, Simpson EK, Li C, Webster ML, Zhu G, Lang S, Chen P, Zeng Q, Ni H 2013 Cardiovasc Hematol Disord Drug Targets View Researchers Other
Introduction to the special issue: Teaching healthcare operations research, part 2 Blake J 2017 INFORMS Transactions on Education View Researchers New or improved product or process
Low-dose decitabine promotes megakaryocyte maturation and platelet production in healthy controls and immune thrombocytopenia Zhou H, Hou Y, Liu X, Qiu J, Feng Q, Wang Y, Zhang X, Min Y, Shao L, Liu X, Li G, Li L, Yang L, Xu S, Ni H, Peng J, Hou M 2015 Thromb Haemost View Researchers Basic research
Microparticles as biomarkers of lung disease - enumeration in biological fluids using lipid bilayer microspheres McVey MJ, Spring C, Semple JW, Maishan M, Kuebler WM 2016 Am J Physiol Lung Cell Mol Physiol View Researchers Basic research
p38MAPK is involved in apoptosis development in apheresis platelet concentrates after riboflavin and ultraviolet light treatment Chen Z, Schubert P, Culibrk B, Devine DV 2014 Transfusion View Researchers Basic research
QSAR accelerated discovery of potent ice recrystallization inhibitors Briard JG, Fernandez M, De Luna P, Woo TK, Ben RN 2016 Sci Rep View Researchers Basic research
Reduction of thrombus size in murine models of thrombosis following administration of recombinant alpha1-proteinase inhibitor mutant proteins Sheffield WP, Eltringham-Smith LJ, Bhakta V, Gataiance S 2012 Thromb Haemost View Researchers Basic research
Riboflavin and ultraviolet light treatment of platelets triggers p38MAPK signaling: inhibition significantly improves in vitro platelet quality after pathogen reduction treatment Schubert P, Coupland D, Culibrk B, Goodrich RP, Devine DV 2013 Transfusion View Researchers Basic research
SHP-1 protein tyrosine phosphatase associates with the adaptor protein CrkL Evren S, Ma XZ, Sakac D, Branch DR 2012 Exp Hematol View Researchers Basic research
Sustained expression of coagulation Factor IX by modified cord blood-derived mesenchymal stromal cells Dodd M, Marquez-Curtis L, Janowska-Wieczorek A, Hortelano G 2014 J Gene Med View Researchers Basic research
The procoagulant envelope virus surface: contribution to enhanced infection Pryzdial EL, Sutherland MR, Ruf W 2014 Thromb Res View Researchers Basic research
Toward a prophylaxis against fetal and neonatal alloimmune thrombocytopenia: induction of antibody-mediated immune suppression and prevention of severe clinical complications in a murine model Tiller H, Killie MK, Chen P, Eksteen M, Husebekk A, Skogen B, Kjeldsen-Kragh J, Ni H 2012 Transfusion View Researchers Basic research
Unexpected suppression of anti-Fya and prevention of hemolytic disease of the fetus and newborn after administration of Rh immune globulin Branch DR, Scofield TL, Moulds JJ, Swanson JL 2011 Transfusion View Researchers Basic research
Changes in minimum hemoglobin and interdonation interval: impact on donor hemoglobin and donation frequency Goldman M, Yi Q-L, Steed T, O'Brien SF 2019 Transfusion View Researchers New or improved product or process
The potential role of a turbidimetric heart-type fatty acid-binding protein assay to aid in the interpretation of persistently elevated, non-changing, cardiac troponin I concentrations Kavsak PA, Ainsworth C, Arnold DM, Scott T, Clark L, Ivica J, Mackett K, Whitlock R, Worster A 2018 Clin Biochem View Researchers Basic research
Synthesis of Highly Biocompatible and Temperature-Responsive Physical Gels for Cryopreservation and 3D Cell Culture Nagao M, Sengupta J, Diaz-Dussan D, Adam M, Wu M, Acker J, Ben R, Ishihara K, Zeng H, Miura Y, Narain R 2018 ACS Appl Bio Mater View Researchers Basic research
Transfusion-related acute lung injury (TRALI) Petraszko T 2019 Blood.ca website View Researchers Clinical research
Virus envelope tissue factor promotes infection in mice Sutherland MR, Simon AY, Shanina I, Horwitz MS, Ruf W, Pryzdial ELG 2019 J Thromb Haemost View Researchers Basic research
Model Human ? Thalassemic Erythrocytes: Effect of Unpaired Purified ?-Hemoglobin Chains on Normal Erythrocytes Scott M 2019 Beta Thalassemia View Researchers Basic research
ResearchUnit: Improving quality testing of stem cells for patients Pineault N 2020 Blood.ca website View Researchers New or improved product or process
Trehalose-Based Polyethers for Cryopreservation and Three-Dimensional Cell Scaffolds Diaz-Dussan D, Peng YY, Sengupta J, Zabludowski R, Adam MK, Acker JP, Ben RN, Kumar P, Narain R 2020 Biomacromolecules View Researchers Basic research
A comparison of methods for prediction of pharmacokinetics when switching to extended half-life products in hemophilia A patients Yu JK, Iorio A, Edginton AN 2020 Thromb Res View Researchers Clinical research
Donor-dependent aging of young and old red blood cell subpopulations: Metabolic and functional heterogeneity Mykhailova O, Olafson C, Turner TR, D?Alessandro A, Acker JP 2020 Transfusion View Researchers Basic research
High subzero cryofixation: A technique for observing ice within tissues Lautner L, William N, Acker JP 2020 Cryobiology View Researchers New or improved product or process
The mega-importance of de novo lipogenesis in platelet production Nazy I, Arnold DM, Steinberg GR 2020 Nat Metab View Researchers Basic research
The impact of extended half-life factor concentrates on patient reported health outcome measures in persons with hemophilia A and hemophilia B Sun HL, Yang M, Poon MC, Lee A, Robinson KS, Sholzberg M, Wu J, Iorio A, Blanchette V, Carcao M, Klaassen RJ, Jackson S 2021 Res Pract Thromb Haemost View Researchers Clinical research
Assessment of bacterial growth in leukoreduced cold-stored whole blood supports overnight hold at room temperature prior to filtration: A pilot study Ramirez-Arcos S, Kou Y, Kumaran D, Culibrk B, Stewart T, Schubert P, McTaggart K 2022 Vox Sang View Researchers New or improved product or process
Heterogeneity of Vaccine-Induced Immune Thrombotic Thrombocytopenia after ChAdOx1 nCoV-19 Vaccination and Safety of Second Vaccination with BNT162b2 Lindhoff-Last E, Schoenborn L, Piorkowski M, Herold J, Greinacher A, Sheppard JA, Warkentin TE 2022 Thromb Haemost View Researchers Clinical research
Blood unit segments accurately represent the biophysical properties of red blood cells in blood bags but not hemolysis Islamzada E, Matthews K, Lamoureux E, Duffy SP, Scott MD, Ma H 2022 Transfusion View Researchers Basic research
Combined preoperative plasma exchange and red blood cell exchange transfusion in a renal transplant patient with protein S deficiency and hemoglobin SC disease Cook O, Cervi A, Laureano M, Gangji AS, Verhovsek M 2021 Transfus Apher Sci View Researchers Clinical research
Concentré de recherche: Suggestion concernant le mécanisme en jeu dans la thrombocytopénie thrombotique induite par le vaccin Batarfi K 2021 Blood.ca website View Researchers Clinical research
Donor-recipient sex is associated with transfusion-related outcomes in critically ill patients Alshalani A, Uhel F, Cremer OL, Schultz MJ, de Vooght KMK, van Bruggen R, Acker JP, Juffermans NP, on behalf of the MARS Consortium 2022 Blood Adv View Researchers Clinical research
Lessons learned from the CONCOR-1 trial Callum J, Bégin P, Jamula E, Liu Y, Kron AT, Auclair MC, Cushing M, Arnold DM 2023 Transfus Med View Researchers Clinical research
A Portrait of Cord Blood Units Distributed for Transplantation from Canadian Blood Services’ Cord Blood Bank: First Analysis Parmar G, Green M, Mostert K, Lawless T, Dibdin N, Weiss J, Ganz K, Petraszko T, Seftel MD, Allan DS 2022 Curr Oncol View Researchers Benchmarking and standard setting
An analysis of the bias in red blood cell hemolysis measurement using several analytical approaches Acker JP, Croteau IM, Yi QL 2012 Clin Chim Acta View Researchers New or improved product or process
CD4+ T-cells are unable to express the HIV natural resistance factor globotriosylceramide Kim M, Binnington B, Sakac D, Lingwood CA, Branch DR 2013 AIDS View Researchers Basic research
Developing highly active small molecule ice recrystallization inhibitors based upon C-linked antifreeze glycoprotein analogues Trant JF, Briggs RA, Capicciotti C, Ben RN 2013 RSC Adv View Researchers Basic research
Donor iron policy: from research to practice O'Brien SF 2016 Transfusion View Researchers New or improved product or process
Enhanced Cell Surface Polymer Grafting in Concentrated and Nonreactive Aqueous Polymer Solutions Rossi NAA, Constantinescu I, Brooks DE, Scott MD, Kizhakkedathu JN 2010 J Am Chem Soc View Researchers Basic research
Fluids in sepsis and septic shock (FISSH): protocol for a pilot randomised controlled trial Rochwerg B, Millen T, Austin P, Zeller M, D'Aragon F, Jaeschke R, Masse MH, Mehta S, Lamontagne F, Meade M, Guyatt G, Cook DJ 2017 BMJ Open View Researchers Clinical research
Hepatoprotective effects of Poly-[hemoglobin-superoxide dismutase-catalase-carbonic anhydrase] on alcohol-damaged primary rat hepatocyte culture in vitro Jiang W, Bian Y, Wang Z, Chang TMS 2016 Artif Cells Nanomed Biotechnol View Researchers New or improved product or process
Immunogenicity, efficacy and safety of Nuwiq® (human-cl rhFVIII) in previously untreated patients with severe haemophilia A-Interim results from the NuProtect Study Liesner RJ, Abashidze M, Aleinikova O, Altisent C, Belletrutti MJ, Borel-Derlon A, Carcao M, Chambost H, Chan AKC, Dubey L, Ducore J, Fouzia NA, Gattens M, Gruel Y, Guillet B, Kavardakova N, El Khorassani M, Klukowska A, Lambert T, Lohade S, Sigaud M, Turea V, Wu JKM, Vdovin V, Pavlova A, Jansen M, Belyanskaya L, Walter O, Knaub S, Neufeld EJ 2017 Haemophilia View Researchers Clinical research
Influence of polymer architecture on antigens camouflage, CD47 protection and complement mediated lysis of surface grafted red blood cells Chapanian R, Constantinescu I, Rossi NA, Medvedev N, Brooks DE, Scott MD, Kizhakkedathu JN 2012 Biomaterials View Researchers Basic research
MDM2 antagonist nutlin plus proteasome inhibitor velcade combination displays a synergistic anti-myeloma activity Saha MN, Jiang H, Jayakar J, Reece D, Branch DR, Chang H 2010 Cancer Biol Ther View Researchers Basic research
Nouvelle cuisine: platelets served with inflammation Kapur R, Zufferey A, Boilard E, Semple JW 2015 J Immunol View Researchers Basic research
Targeting activated platelets and fibrinolysis: hitting two birds with one stone Reheman A, Xu X, Reddy EC, Ni H 2014 Circ Res View Researchers Basic research
Screening of red blood cells for extracellular vesicle content as a product quality indicator Acker JP, Almizraq RJ, Millar D, Maurer-Spurej E 2018 Transfusion View Researchers New or improved product or process